The orphan nuclear receptor SHP inhibits agonist-dependent transcriptional activity of estrogen receptors ERalpha and ERbeta.
about
Functional conservation of interactions between a homeodomain cofactor and a mammalian FTZ-F1 homologueA transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHPSynergistic activation of the human orphan nuclear receptor SHP gene promoter by basic helix-loop-helix protein E2A and orphan nuclear receptor SF-1Suppression of estrogen receptor-mediated transcription and cell growth by interaction with TR2 orphan receptorLXXLL motifs and AF-2 domain mediate SHP (NR0B2) homodimerization and DAX1 (NR0B1)-DAX1A heterodimerizationMutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjectsThe orphan nuclear receptor SHP utilizes conserved LXXLL-related motifs for interactions with ligand-activated estrogen receptorsThe orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repressionMultiple domains of the Receptor-Interacting Protein 140 contribute to transcription inhibitionBile acids inhibit duodenal secretin expression via orphan nuclear receptor small heterodimer partner (SHP)Advances in estrogen receptor biology: prospects for improvements in targeted breast cancer therapyEID3 is a novel EID family member and an inhibitor of CBP-dependent co-activationInsights into Orphan Nuclear Receptors as Prognostic Markers and Novel Therapeutic Targets for Breast CancerCloning and characterization of RAP250, a novel nuclear receptor coactivatorModulation of estrogen receptor-mediated transactivation by orphan receptor TR4 in MCF-7 cellsGlucocorticoid signaling is perturbed by the atypical orphan receptor and corepressor SHPSmall heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivationTruncated estrogen receptor product-1 stimulates estrogen receptor alpha transcriptional activity by titration of repressor proteinsTruncated estrogen receptor product-1 suppresses estrogen receptor transactivation by dimerization with estrogen receptors alpha and beta.Role of nuclear receptor SHP in metabolism and cancer.The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male mice.Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors alpha and beta.A protein interaction atlas for the nuclear receptors: properties and quality of a hub-based dimerisation network.All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade.Adamantyl-substituted retinoid-related molecules bind small heterodimer partner and modulate the Sin3A repressor.Regulation of cytochrome P450 (CYP) genes by nuclear receptors.Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner.Differential regulation of the orphan nuclear receptor small heterodimer partner (SHP) gene promoter by orphan nuclear receptor ERR isoforms.AMPK-dependent repression of hepatic gluconeogenesis via disruption of CREB.CRTC2 complex by orphan nuclear receptor small heterodimer partner.Estrogen receptor alpha regulates expression of the orphan receptor small heterodimer partner.Liver receptor homolog 1 controls the expression of carboxyl ester lipase.Orphan nuclear receptors as eLiXiRs and FiXeRs of sterol metabolism.LXXLL-related motifs in Dax-1 have target specificity for the orphan nuclear receptors Ad4BP/SF-1 and LRH-1.Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism.The orphan nuclear receptor small heterodimer partner is required for thiazolidinedione effects in leptin-deficient mice.A pleiotropic role for the orphan nuclear receptor small heterodimer partner in lipid homeostasis and metabolic pathways.Estrogenic regulation of the GnRH neuronCross-talk between xenobiotic detoxication and other signalling pathways: clinical and toxicological consequences.Liver receptor homolog-1 (LRH-1): a potential therapeutic target for cancerOrphan nuclear receptors in breast cancer pathogenesis and therapeutic response.
P2860
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P2860
The orphan nuclear receptor SHP inhibits agonist-dependent transcriptional activity of estrogen receptors ERalpha and ERbeta.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
The orphan nuclear receptor SH ...... receptors ERalpha and ERbeta.
@en
type
label
The orphan nuclear receptor SH ...... receptors ERalpha and ERbeta.
@en
prefLabel
The orphan nuclear receptor SH ...... receptors ERalpha and ERbeta.
@en
P2093
P2860
P356
P1476
The orphan nuclear receptor SH ...... receptors ERalpha and ERbeta.
@en
P2093
Damdimopoulos AE
Gustafsson JA
Johansson L
Thomsen JS
P2860
P304
P356
10.1074/JBC.274.1.345
P407
P577
1999-01-01T00:00:00Z