Crystal structure of lumazine synthase from Mycobacterium tuberculosis as a target for rational drug design: binding mode of a new class of purinetrione inhibitors.
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Lumazine synthase from Candida albicans as an anti-fungal target enzyme: structural and biochemical basis for drug designStructural study and thermodynamic characterization of inhibitor binding to lumazine synthase fromBacillus anthracisCatalysis product captured in lumazine synthase from the fungal pathogen Candida glabrataAnalyses of the Binding between Water Soluble C60 Derivatives and Potential Drug Targets through a Molecular Docking ApproachVirtual screening, selection and development of a benzindolone structural scaffold for inhibition of lumazine synthaseA new measure for functional similarity of gene products based on Gene OntologyDiscovery and development of a small molecule library with lumazine synthase inhibitory activity.Genetic control of biosynthesis and transport of riboflavin and flavin nucleotides and construction of robust biotechnological producers.O-Nucleoside, S-nucleoside, and N-nucleoside probes of lumazine synthase and riboflavin synthase.A novel lumazine synthase inhibitor derived from oxidation of 1,3,6,8-tetrahydroxy-2,7-naphthyridine to a tetraazaperylenehexaone derivative.Survey of large protein complexes in D. vulgaris reveals great structural diversity.Biosynthesis of vitamin B2: a unique way to assemble a xylene ring.The lumazine synthase/riboflavin synthase complex: shapes and functions of a highly variable enzyme system.The eradication of leprosy: molecular modeling techniques for novel drug discovery.Evolution of vitamin B2 biosynthesis: 6,7-dimethyl-8-ribityllumazine synthases of Brucella.Improvement of the quality of lumazine synthase crystals by protein engineering.Development of new antituberculous agents based on new drug targets and structure-activity relationship.Design, synthesis, and biochemical evaluation of 1,5,6,7-tetrahydro-6,7-dioxo-9-D-ribitylaminolumazines bearing alkyl phosphate substituents as inhibitors of lumazine synthase and riboflavin synthase.The C-terminal peptide of Aquifex aeolicus riboflavin synthase directs encapsulation of native and foreign guests by a cage-forming lumazine synthase.Crystal structure of an archaeal pentameric riboflavin synthase in complex with a substrate analog inhibitor: stereochemical implications.Sensing the dissociation of a polymeric enzyme by means of an engineered intrinsic probe.Identification of potent chromone embedded [1,2,3]-triazoles as novel anti-tubercular agents.Analyses of cobalt–ligand and potassium–ligand bond lengths in metalloproteins: trends and patterns
P2860
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P2860
Crystal structure of lumazine synthase from Mycobacterium tuberculosis as a target for rational drug design: binding mode of a new class of purinetrione inhibitors.
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
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2005年學術文章
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2005年學術文章
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name
Crystal structure of lumazine ...... ss of purinetrione inhibitors.
@en
type
label
Crystal structure of lumazine ...... ss of purinetrione inhibitors.
@en
prefLabel
Crystal structure of lumazine ...... ss of purinetrione inhibitors.
@en
P2093
P921
P356
P1433
P1476
Crystal structure of lumazine ...... ss of purinetrione inhibitors.
@en
P2093
Boris Illarionov
Ekaterina Morgunova
Guangyi Jin
Ilka Haase
Mark Cushman
Markus Fischer
Rudolf Ladenstein
Winfried Meining
P304
P356
10.1021/BI047848A
P407
P577
2005-03-01T00:00:00Z