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Notch signaling deregulation in multiple myeloma: A rational molecular targetNotch is a critical regulator in cervical cancer by regulating Numb splicing.Biological significance and therapeutic implication of resveratrol-inhibited Wnt, Notch and STAT3 signaling in cervical cancer cellsNotch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient miceThe different role of Notch1 and Notch2 in astrocytic gliomasThe NOTCH signaling pathway in normal and malignant blood cell production.Evidence for functional redundancy between C. elegans ADAM proteins SUP-17/Kuzbanian and ADM-4/TACETetrandrine induces autophagy and differentiation by activating ROS and Notch1 signaling in leukemia cells.Notch signalling drives bone marrow stromal cell-mediated chemoresistance in acute myeloid leukemiaNotch 2 signaling contributes to cell growth, anti-apoptosis and metastasis in laryngeal squamous cell carcinomaMechanisms and clinical prospects of Notch inhibitors in the therapy of hematological malignancies.Multiple myeloma-derived Jagged ligands increases autocrine and paracrine interleukin-6 expression in bone marrow niche.In silico evidence of signaling pathways of notch mediated networks in leukemia.Mechanisms controlling hematopoietic stem cell functions during normal hematopoiesis and hematological malignancies.Ikaros and tumor suppression in acute lymphoblastic leukemiaNotch-directed microenvironment reprogramming in myeloma: a single path to multiple outcomes.The challenge of targeting notch in hematologic malignancies.Potential therapeutic targets and small molecular drugs for pediatric B-precursor acute lymphoblastic leukemia treatment based on microarray dataHeparan sulfate D-glucosaminyl 3-O-sulfotransferase-3B1 (HS3ST3B1) promotes angiogenesis and proliferation by induction of VEGF in acute myeloid leukemia cells.Notch signaling drives multiple myeloma induced osteoclastogenesis.Notch activation inhibits AML growth and survival: a potential therapeutic approach.Notch1 signaling is irresponsible to the anti-leukemic effect of HDACis in B-ALL Nalm-6 cells.Notch1 promotes survival of E2A-deficient T cell lymphomas through pre-T cell receptor-dependent and -independent mechanisms.The emerging roles of Notch signaling in leukemia and stem cells.Activation of Notch signal pathway is associated with a poorer prognosis in acute myeloid leukemia.Jagged-1: a new promising factor associated with favorable prognosis in patients with acute myeloid leukemia.PI3K/AKT signaling inhibits NOTCH1 lysosome-mediated degradation.NOTCH1 mutations are rare in acute myeloid leukemia.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
A wide role for NOTCH1 signaling in acute leukemia.
@en
type
label
A wide role for NOTCH1 signaling in acute leukemia.
@en
prefLabel
A wide role for NOTCH1 signaling in acute leukemia.
@en
P2093
P1433
P1476
A wide role for NOTCH1 signaling in acute leukemia.
@en
P2093
Andrea Basile
Andrea Biondi
Elisabetta Calzavara
Paola Comi
Raffaella Chiaramonte
Valentina Cecchinato
Vincenzo Rossi
P304
P356
10.1016/J.CANLET.2004.07.022
P407
P50
P577
2005-02-01T00:00:00Z