Comparison of binding of mixed ribose-deoxyribose analogues of CUCU to a ribozyme and to GGAGAA by equilibrium dialysis: evidence for ribozyme specific interactions with 2' OH groups.
about
Predicting oligonucleotide affinity to nucleic acid targets.A conserved pseudouridine modification in eukaryotic U2 snRNA induces a change in branch-site architectureCoaxial stacking of helixes enhances binding of oligoribonucleotides and improves predictions of RNA foldingA relaxed active site after exon ligation by the group I intronNMR structure of a 4 x 4 nucleotide RNA internal loop from an R2 retrotransposon: Identification of a three purine-purine sheared pair motif and comparison to MC-SYM predictionsThree metal ions at the active site of the Tetrahymena group I ribozymeIn vitro suicide inhibition of self-splicing of a group I intron from Pneumocystis carinii by an N3' --> P5' phosphoramidate hexanucleotideMinor groove recognition of the conserved G.U pair at the Tetrahymena ribozyme reaction site.Mapping of accessible sites for oligonucleotide hybridization on hepatitis delta virus ribozymesIn vitro trans-splicing in Saccharomyces cerevisiaeSite-specific deoxynucleotide substitutions in yeast U6 snRNA block splicing of pre-mRNA in vitro.Oligonucleotide directed misfolding of RNA inhibits Candida albicans group I intron splicingSequence specificity of in vivo reverse splicing of the Tetrahymena group I intronUse of binding energy by an RNA enzyme for catalysis by positioning and substrate destabilization.A minor groove RNA triple helix within the catalytic core of a group I intron.2'-Fluoro substituents can mimic native 2'-hydroxyls within structured RNA.Structure-function analysis from the outside in: long-range tertiary contacts in RNA exhibit distinct catalytic roles.An active site rearrangement within the Tetrahymena group I ribozyme releases nonproductive interactions and allows formation of catalytic interactions.Cooperative and anticooperative binding to a ribozyme.Use of intrinsic binding energy for catalysis by an RNA enzymeOptical melting measurements of nucleic acid thermodynamics.Novel system for analysis of group I 3' splice site reactions based on functional trans-interaction of the P1/P10 reaction helix with the ribozyme's catalytic core.A rearrangement of the guanosine-binding site establishes an extended network of functional interactions in the Tetrahymena group I ribozyme active site.Molecular recognition properties of IGS-mediated reactions catalyzed by a Pneumocystis carinii group I intron.The contribution of 2'-hydroxyls to the cleavage activity of the Neurospora VS ribozyme.Folding of the HDV antigenomic ribozyme pseudoknot structure deduced from long-range photocrosslinks.Structure and function converge to identify a hydrogen bond in a group I ribozyme active site.Folding of DNA substrate-hairpin ribozyme domains: use of deoxy 4-thiouridine as an intrinsic photolabel.Crystal structure of a group I intron splicing intermediate.Functional identification of ligands for a catalytic metal ion in group I intronsTightening of active site interactions en route to the transition state revealed by single-atom substitution in the guanosine-binding site of the Tetrahymena group I ribozyme.
P2860
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P2860
Comparison of binding of mixed ribose-deoxyribose analogues of CUCU to a ribozyme and to GGAGAA by equilibrium dialysis: evidence for ribozyme specific interactions with 2' OH groups.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh
1991年學術文章
@zh-hant
name
Comparison of binding of mixed ...... nteractions with 2' OH groups.
@en
type
label
Comparison of binding of mixed ...... nteractions with 2' OH groups.
@en
prefLabel
Comparison of binding of mixed ...... nteractions with 2' OH groups.
@en
P356
P1433
P1476
Comparison of binding of mixed ...... nteractions with 2' OH groups.
@en
P2093
Bevilacqua PC
P304
10632-10640
P356
10.1021/BI00108A005
P407
P577
1991-11-01T00:00:00Z