Human alpha1,3/4-fucosyltransferases. I. Identification of amino acids involved in acceptor substrate binding by site-directed mutagenesis.
about
Human alpha 1,3/4 fucosyltransferases. Characterization of highly conserved cysteine residues and N-linked glycosylation sitesAncestral exonic organization of FUT8, the gene encoding the alpha6-fucosyltransferase, reveals successive peptide domains which suggest a particular three-dimensional core structure for the alpha6-fucosyltransferase family.Site-specific fucosylation of sialylated polylactosamines by alpha1,3/4-fucosyltransferases-V and -VI Is defined by amino acids near the N terminus of the catalytic domain.Identification of essential amino acids in the Azorhizobium caulinodans fucosyltransferase NodZ.C-terminal amino acids of Helicobacter pylori alpha1,3/4 fucosyltransferases determine type I and type II transfer.Fucosylation in prokaryotes and eukaryotes.Structure/function analysis of Pasteurella multocida heparosan synthases: toward defining enzyme specificity and engineering novel catalysts.Site-directed mutagenesis of glutamate 317 of bovine alpha-1,3Galactosyltransferase and its effect on enzyme activity: implications for reaction mechanismPurification, kinetic characterization, and mapping of the minimal catalytic domain and the key polar groups of Helicobacter pylori alpha-(1,3/1,4)-fucosyltransferases.Human alpha1,3/4-fucosyltransferases. III. A Lys/Arg residue located within the alpha1,3-FucT motif is required for activity but not substrate binding.N-glycosylations of human α1,3-fucosyltransferase IX are required for full enzyme activity.Alpha1,4-fucosyltransferase activity: a significant function in the primate lineage has appeared twice independently.Highly conserved cysteines of mouse core 2 beta1,6-N-acetylglucosaminyltransferase I form a network of disulfide bonds and include a thiol that affects enzyme activity.A single aromatic amino acid at the carboxyl terminus of Helicobacter pylori {alpha}1,3/4 fucosyltransferase determines substrate specificity.
P2860
Q28144622-CD40AE0E-6663-4DB4-AC6E-C8D3D2CC947FQ30168637-678324F4-945E-4ABF-AB49-31DB6243EC28Q30981908-11037154-3110-43DF-BB83-DD4E60432EBDQ33997185-E80ADB7D-98BA-4647-8B88-CDBB9640A0B3Q34188500-F16AC9C6-5F27-4C3E-B09D-B872F6FE3933Q34566205-2F6252D6-1843-4F73-9B1E-A01F9A4343EDQ35801995-9FC4D8C3-DAC3-487F-A2E0-21C1B1BA65CAQ36017111-370A3B30-493A-4E87-A229-BD4F7EFFC639Q38316898-9787F234-83B4-4122-BFC4-7771A9991ACAQ38333345-DBF245E3-CF24-45E5-8E22-C2F582CBC126Q42010489-DC4726F3-B705-4DA7-96E0-C1D497E88806Q44007526-D1214BBE-5075-4B8D-B624-2EEEE2E23FBEQ44572798-1A6DEE0F-B456-4351-912F-74AFF9B08130Q46693385-159A94FB-7520-48E4-8364-5104D7920EAE
P2860
Human alpha1,3/4-fucosyltransferases. I. Identification of amino acids involved in acceptor substrate binding by site-directed mutagenesis.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Human alpha1,3/4-fucosyltransf ...... by site-directed mutagenesis.
@en
type
label
Human alpha1,3/4-fucosyltransf ...... by site-directed mutagenesis.
@en
prefLabel
Human alpha1,3/4-fucosyltransf ...... by site-directed mutagenesis.
@en
P2093
P2860
P356
P1476
Human alpha1,3/4-fucosyltransf ...... by site-directed mutagenesis.
@en
P2093
P2860
P304
25244-25249
P356
10.1074/JBC.273.39.25244
P407
P577
1998-09-01T00:00:00Z