Induction of apoptosis by proteasome inhibitors in B-CLL cells is associated with downregulation of CD23 and inactivation of Notch2.
about
γ-Secretase inhibitor enhances antitumour effect of radiation in Notch-expressing lung cancerPhase I/II study of single-agent bortezomib for the treatment of patients with myelofibrosis. Clinical and biological effects of proteasome inhibition.Phase II study of dasatinib in relapsed or refractory chronic lymphocytic leukemia.Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim.The canonical Notch signaling was involved in the regulation of intestinal epithelial cells apoptosis after intestinal ischemia/reperfusion injury.Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies.Candidate Agtr2 influenced genes and pathways identified by expression profiling in the developing brain of Agtr2(-/y) mice.Development of beta-amyloid-induced neurodegeneration in Alzheimer's disease and novel neuroprotective strategies.Cross talk between EBV and telomerase: the role of TERT and NOTCH2 in the switch of latent/lytic cycle of the virusClinical trials with anti-angiogenic agents in hematological malignancies.p53 and Notch signaling in chronic lymphocytic leukemia: clues to identifying novel therapeutic strategies.B-cell antigen receptor signaling in chronic lymphocytic leukemia: therapeutic targets and translational opportunities.The Central Role for Microenvironment in B-Cell Malignancies: Recent Insights into Synergistic Effects of its Therapeutic Targeting and Anti-CD20 Antibodies.Inhibition of Notch and HIF enhances the antitumor effect of radiation in Notch expressing lung cancer.Combined antitumor effect of γ-secretase inhibitor and ABT-737 in Notch-expressing non-small cell lung cancer.Gliotoxin is a potent NOTCH2 transactivation inhibitor and efficiently induces apoptosis in chronic lymphocytic leukaemia (CLL) cells.Bortezomib-mediated inhibition of steroid receptor coactivator-3 degradation leads to activated Akt.Dietary flavonoids inhibit the anticancer effects of the proteasome inhibitor bortezomib.Combined proteasome and Bcl-2 inhibition stimulates apoptosis and inhibits growth in EBV-transformed lymphocytes: a potential therapeutic approach to EBV-associated lymphoproliferative diseases.The sesquiterpene lactone parthenolide induces selective apoptosis of B-chronic lymphocytic leukemia cells in vitro.The emerging roles of Notch signaling in leukemia and stem cells.(Immuno)proteasomes as therapeutic target in acute leukemia.NOTCH1 Aberrations in Chronic Lymphocytic Leukemia.
P2860
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P2860
Induction of apoptosis by proteasome inhibitors in B-CLL cells is associated with downregulation of CD23 and inactivation of Notch2.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Induction of apoptosis by prot ...... 23 and inactivation of Notch2.
@en
type
label
Induction of apoptosis by prot ...... 23 and inactivation of Notch2.
@en
prefLabel
Induction of apoptosis by prot ...... 23 and inactivation of Notch2.
@en
P2093
P2860
P356
P1433
P1476
Induction of apoptosis by prot ...... 23 and inactivation of Notch2.
@en
P2093
Duechler M
Hilgarth M
Schwarzmeier JD
P2860
P2888
P304
P356
10.1038/SJ.LEU.2403592
P577
2005-02-01T00:00:00Z
P5875
P6179
1043396274