Transactivation of the human apolipoprotein CII promoter by orphan and ligand-dependent nuclear receptors. The regulatory element CIIC is a thyroid hormone response element.
about
Expression and localization of P1 promoter-driven hepatocyte nuclear factor-4alpha (HNF4alpha) isoforms in human and ratsCREB-binding protein is a transcriptional coactivator for hepatocyte nuclear factor-4 and enhances apolipoprotein gene expressionTranscriptional regulation of the human hepatic lipase (LIPC) gene promoterThyroid hormone regulates the hypotriglyceridemic gene APOA5Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasisStructural basis for HNF-4alpha activation by ligand and coactivator binding.STAT1 interacts with RXRα to upregulate ApoCII gene expression in macrophages.Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors.Defective ureagenesis in mice carrying a liver-specific disruption of hepatocyte nuclear factor 4alpha (HNF4alpha ). HNF4alpha regulates ornithine transcarbamylase in vivo.The activation function-1 of hepatocyte nuclear factor-4 is an acidic activator that mediates interactions through bulky hydrophobic residues.Synergism between nuclear receptors bound to specific hormone response elements of the hepatic control region-1 and the proximal apolipoprotein C-II promoter mediate apolipoprotein C-II gene regulation by bile acids and retinoids.Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha.Activation of the nuclear receptor FXR induces fibrinogen expression: a new role for bile acid signaling.Critical role of residues defining the ligand binding pocket in hepatocyte nuclear factor-4alpha.Disruption of TR4 orphan nuclear receptor reduces the expression of liver apolipoprotein E/C-I/C-II gene cluster.Role of hepatocyte nuclear factor-4alpha in transcriptional regulation of C1qTNF-related protein 5 in the liver.Apolipoprotein C-II: New findings related to genetics, biochemistry, and role in triglyceride metabolism.
P2860
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P2860
Transactivation of the human apolipoprotein CII promoter by orphan and ligand-dependent nuclear receptors. The regulatory element CIIC is a thyroid hormone response element.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Transactivation of the human a ...... roid hormone response element.
@en
type
label
Transactivation of the human a ...... roid hormone response element.
@en
prefLabel
Transactivation of the human a ...... roid hormone response element.
@en
P2860
P356
P1476
Transactivation of the human a ...... yroid hormone response element
@en
P2093
D Kardassis
E Sacharidou
P2860
P304
17810-17816
P356
10.1074/JBC.273.28.17810
P407
P577
1998-07-01T00:00:00Z