Oligodeoxynucleotides lacking CpG dinucleotides mediate Toll-like receptor 9 dependent T helper type 2 biased immune stimulation.
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The effect of TLR9 agonist CpG oligodeoxynucleotides on the intestinal immune response of cobia (Rachycentron canadum).Conditional immortalization of human B cells by CD40 ligation.Requirement for DNA CpG content in TLR9-dependent dendritic cell activation induced by DNA-containing immune complexesSystematic CpT (ApG) depletion and CpG excess are unique genomic signatures of large DNA viruses infecting invertebrates.Spontaneous production of immunoglobulin M in human epithelial cancer cellsPotential capacity of aptamers to trigger immune activation in human blood.In vitro test system for evaluation of immune activation potential of new single-stranded DNA-based therapeutics.Inhibitory oligodeoxynucleotides - therapeutic promise for systemic autoimmune diseases?Progress in drug development of immunostimulatory CpG oligodeoxynucleotide ligands for TLR9.CpG oligodeoxynucleotides induce cyclooxygenase-2 in human B lymphocytes: implications for adjuvant activity and antibody production.Targeting Toll-like receptor signaling in plasmacytoid dendritic cells and autoreactive B cells as a therapy for lupus.Targeted nanoparticle delivery overcomes off-target immunostimulatory effects of oligonucleotides and improves therapeutic efficacy in chronic lymphocytic leukemia.TLR9 in health and disease.Development of TLR9 agonists for cancer therapyTLR2, TLR4 and TLR9 genotypes and haplotypes in the susceptibility to and clinical course of Chlamydia trachomatis infections in Dutch women.Pleiotropic action of CpG-ODN on endothelium and macrophages attenuates angiogenesis through distinct pathways.Toll-like receptor 9-dependent activation of myeloid dendritic cells by Deoxynucleic acids from Candida albicans.Topical CpG adjuvantation of a protein-based vaccine induces protective immunity to Listeria monocytogenes.Imprinted DC mediate the immune-educating effect of early-life microbial exposure.Extended sequence preferences for oligodeoxyribonucleotide activity.Toll-Like Receptors and Tissue Remodeling: The Pro/Cons Recent Findings.The effects of CpG-ODNs and Chitosan adjuvants on the elicitation of immune responses induced by the HIV-1-Tat-based candidate vaccines in mice.Immunostimulatory effects of three classes of CpG oligodeoxynucleotides on PBMC from HCV chronic carriers.Oligodeoxynucleotides inhibit Toll-like receptor 3 mediated cytotoxicity and CXCL8 release in keratinocytes.VaccineDA: Prediction, design and genome-wide screening of oligodeoxynucleotide-based vaccine adjuvants.Oligonucleotides suppress PKB/Akt and act as superinductors of apoptosis in human keratinocytes.Distinct immunological activation profiles of dSLIM® and ProMune® depend on their different structural context.Impact of class A, B and C CpG-oligodeoxynucleotides on in vitro activation of innate immune cells in human immunodeficiency virus-1 infected individuals.Suppression of Th1- and Th2-type immune responses in infant mouse spleen after prenatal and postnatal exposure to low-level toluene and peptidoglycan.Structure-efficacy relationships of immunostimulatory activity of CpG-containing oligodeoxynucleotides on mouse spleen cells.Targeting Myeloid-Derived Suppressor Cells in Cancer.Therapeutic Targeting of Long Non-Coding RNAs in Cancer.Strong immunostimulatory activity of AT-oligodeoxynucleotide requires a six-base loop with a self-stabilized 5'-C...G-3' stem structure.Anti-miRNA oligonucleotides: A comprehensive guide for design.Bacterial DNA containing methylated CpG motifs retains immunostimulatory activity in synergy with modified lipopolysaccharides.Effect of natural commensal-origin DNA on toll-like receptor 9 (TLR9) signaling cascade, chemokine IL-8 expression, and barrier integritiy of polarized intestinal epithelial cells.
P2860
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P2860
Oligodeoxynucleotides lacking CpG dinucleotides mediate Toll-like receptor 9 dependent T helper type 2 biased immune stimulation.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Oligodeoxynucleotides lacking ...... e 2 biased immune stimulation.
@en
type
label
Oligodeoxynucleotides lacking ...... e 2 biased immune stimulation.
@en
prefLabel
Oligodeoxynucleotides lacking ...... e 2 biased immune stimulation.
@en
P2093
P2860
P1433
P1476
Oligodeoxynucleotides lacking ...... e 2 biased immune stimulation.
@en
P2093
Arthur M Krieg
Christian Schetter
Heather L Davis
Jörg Vollmer
Marion Jurk
Michael J McCluskie
Paul Payette
Risini D Weeratna
Ulrike Samulowitz
P2860
P304
P356
10.1111/J.1365-2567.2004.01962.X
P577
2004-10-01T00:00:00Z