Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo.
about
Co-ordination of cell cycle and differentiation in the developing nervous systemSnail2/Slug cooperates with Polycomb repressive complex 2 (PRC2) to regulate neural crest development.The dual roles of geminin during trophoblast proliferation and differentiationGeminin loss causes neural tube defects through disrupted progenitor specification and neuronal differentiation.Geminin is required for zygotic gene expression at the Xenopus mid-blastula transition.Neural transcription factors: from embryos to neural stem cells.Geminin is required for the maintenance of pluripotency.Establishing pluripotency in early development.Regulation of DNA replication during development.The epigenome in early vertebrate development.Distinct activities of the anaphase-promoting complex/cyclosome (APC/C) in mouse embryonic cells.Multicilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiationEnhancers: emerging roles in cell fate specificationOn becoming neural: what the embryo can tell us about differentiating neural stem cells.Links between DNA Replication, Stem Cells and Cancer.Nervous decision-making: to divide or differentiate.Cell cycle regulation of proliferation versus differentiation in the central nervous system.Retinoic acid signaling and neuronal differentiation.Concise Review: Geminin-A Tale of Two Tails: DNA Replication and Transcriptional/Epigenetic Regulation in Stem Cells.Cell Cycle Remodeling and Zygotic Gene Activation at the Midblastula Transition.Gene regulatory networks in neural cell fate acquisition from genome-wide chromatin association of Geminin and Zic1Geminin promotes an epithelial-to-mesenchymal transition in an embryonic stem cell model of gastrulation.Geminin regulates the transcriptional and epigenetic status of neuronal fate-promoting genes during mammalian neurogenesisGeminin restrains mesendodermal fate acquisition of embryonic stem cells and is associated with antagonism of Wnt signaling and enhanced polycomb-mediated repression.Geminin escapes degradation in G1 of mouse pluripotent cells and mediates the expression of Oct4, Sox2, and NanogSpotlight on geminin.Geminin deficiency enhances survival in a murine medulloblastoma model by inducing apoptosis of preneoplastic granule neuron precursors.Dual roles of Akirin2 protein during Xenopus neural development.
P2860
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P2860
Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
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2010年學術文章
@zh-hant
name
Geminin cooperates with Polyco ...... ommitment in the early embryo.
@en
type
label
Geminin cooperates with Polyco ...... ommitment in the early embryo.
@en
prefLabel
Geminin cooperates with Polyco ...... ommitment in the early embryo.
@en
P2093
P2860
P356
P1433
P1476
Geminin cooperates with Polyco ...... ommitment in the early embryo.
@en
P2093
Jason C Mills
Jong-Won Lim
Kristen L Kroll
Pamela Hummert
P2860
P356
10.1242/DEV.059824
P407
P577
2010-11-23T00:00:00Z