Molecular mimicry in diabetes mellitus: the homologous domain in coxsackie B virus protein 2C and islet autoantigen GAD65 is highly conserved in the coxsackie B-like enteroviruses and binds to the diabetes associated HLA-DR3 molecule.
about
The relationship between predicted peptide-MHC class II affinity and T-cell activation in a HLA-DRbeta1*0401 transgenic mouse modelPotential viral pathogenic mechanism in human type 1 diabetesThe pancreas in human type 1 diabetes."Viral déjà vu" elicits organ-specific immune disease independent of reactivity to self.Genes influencing innate and acquired immunity in type 1 diabetes and latent autoimmune diabetes in adults.Type 1 diabetes: etiology, immunology, and therapeutic strategies.Enteroviruses and causality of type 1 diabetes: how close are we?Death waits for no man--does it wait for a virus? How enteroviruses induce and control cell deathMolecular characterization of environmental and clinical echovirus 6 isolates from Poland, 2006-2014.Molecular analysis of an echovirus 3 strain isolated from an individual concurrently with appearance of islet cell and IA-2 autoantibodies.Enterovirus infection can induce immune responses that cross-react with beta-cell autoantigen tyrosine phosphatase IA-2/IAR.Autoreactive T cells in type 1 diabetes.HLA Class II molecules on haplotypes associated with type 1 diabetes exhibit similar patterns of binding affinities for coxsackievirus P2C peptides.Evidence for a locus (IDDM16) in the immunoglobulin heavy chain region on chromosome 14q32.3 producing susceptibility to type 1 diabetes
P2860
Q24795875-DFED4734-FBF4-44AF-9F37-91B5438160D2Q28656023-F7167000-BA76-4491-A5FD-E2A0D67275D5Q34496850-90A82953-1176-45E3-B978-87F95A3025E6Q34520218-EAEE39DB-835B-4CA5-9DD6-2FD8D7DC0483Q36666063-89FC68D2-A5F3-476D-8228-AA38C0ED94A5Q37830198-E6068C5B-F2A1-49D9-8320-5DA2F205D172Q37947366-B3000223-4DC0-4B06-A473-ED53951C18A4Q38244749-BEA9E0D8-47E2-4490-A764-4C9544BD4373Q39296182-DB73FA93-DF53-4F95-8790-629339A60CE3Q42043629-CB63F710-A53F-44A5-9ED6-1615D6BBBD16Q43856153-85BE05DF-D3B8-4A05-8732-47623FFB06A5Q48004838-498A6C31-3601-4FAF-9D62-D66D397C332FQ51987940-84D4F7BF-310B-4D48-B651-7B965726750BQ58201241-E6A1A046-D0F1-42F5-B0ED-14892379BF1C
P2860
Molecular mimicry in diabetes mellitus: the homologous domain in coxsackie B virus protein 2C and islet autoantigen GAD65 is highly conserved in the coxsackie B-like enteroviruses and binds to the diabetes associated HLA-DR3 molecule.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Molecular mimicry in diabetes ...... s associated HLA-DR3 molecule.
@en
type
label
Molecular mimicry in diabetes ...... s associated HLA-DR3 molecule.
@en
prefLabel
Molecular mimicry in diabetes ...... s associated HLA-DR3 molecule.
@en
P2093
P356
P1433
P1476
Molecular mimicry in diabetes ...... s associated HLA-DR3 molecule.
@en
P2093
Melchers WJ
Ottenhoff TH
Vreugdenhil GR
P2888
P356
10.1007/S001250050864
P577
1998-01-01T00:00:00Z
P5875
P6179
1048947298