Targeting the extrinsic apoptotic pathway in cancer: lessons learned and future directions
about
The Janus Face of Death Receptor Signaling during Tumor ImmunoeditingLipopolysaccharides may aggravate apoptosis through accumulation of autophagosomes in alveolar macrophages of human silicosisThe linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death.Enhancing the antitumor efficacy of a cell-surface death ligand by covalent membrane display.Evodiamine inhibits proliferation and induces apoptosis in gastric cancer cells.Oral proteasome inhibitor with strong preclinical efficacy in myeloma models.Danusertib Induces Apoptosis, Cell Cycle Arrest, and Autophagy but Inhibits Epithelial to Mesenchymal Transition Involving PI3K/Akt/mTOR Signaling Pathway in Human Ovarian Cancer Cells.The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and AxlOuabain Enhances ADPKD Cell Apoptosis via the Intrinsic Pathway.Pancreatic cancer stem cells in patient pancreatic xenografts are sensitive to drozitumab, an agonistic antibody against DR5.MicroRNA-related polymorphisms in apoptosis pathway genes are predictive of clinical outcome in patients with limited disease small cell lung cancerIn vitro assessment of a computer-designed potential anticancer agent in cervical cancer cells.Antitherapeutic antibody-mediated hepatotoxicity of recombinant human Apo2L/TRAIL in the cynomolgus monkey.Inhibitory effect of bufalin on retinoblastoma cells (HXO-RB44) via the independent mitochondrial and death receptor pathway.Functional TRAIL receptors in monocytes and tumor-associated macrophages: A possible targeting pathway in the tumor microenvironmentPolymeric mechanical amplifiers of immune cytokine-mediated apoptosis.Systematic network-based discovery of a Fam20C inhibitor (FL-1607) with apoptosis modulation in triple-negative breast cancer.Insights into the involvement of noncoding RNAs in 5-fluorouracil drug resistance.ONC201: Stressing tumors to death.Monitoring drug induced apoptosis and treatment sensitivity in non-small cell lung carcinoma using dielectrophoresis.Apoptosis of human gastric carcinoma cells induced by Euphorbia esula latexExpression of Tim4 in Glioma and its Regulatory Role in LN-18 Glioma Cells.Molecular mechanisms for tumor resistance to chemotherapy.Down-Regulating Receptor Interacting Protein Kinase 1 (RIP1) Promotes Oxaliplatin-Induced Tca8113 Cell Apoptosis.The role of cGMP and its signaling pathways in kidney disease.Lung carcinogenesis and fibrosis taken together: just coincidence?MUC1 induces tamoxifen resistance in estrogen receptor-positive breast cancer.Dyslipidemia and Diabetes Increase the OPG/TRAIL Ratio in the Cardiovascular System.Programmed Death Ligand 1 (PD-L1)-targeted TRAIL combines PD-L1-mediated checkpoint inhibition with TRAIL-mediated apoptosis induction.JWA regulates TRAIL-induced apoptosis via MARCH8-mediated DR4 ubiquitination in cisplatin-resistant gastric cancer cells.NGF sensitizes TrkA SH-SY5Y neuroblastoma cells to TRAIL-induced apoptosis.TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells, unveiling a potential therapeutic "Achilles heel" for the TrkAIII oncoprotein in neuroblastoma."Scar-cinoma": viewing the fibrotic lung mesenchymal cell in the context of cancer biology.Isolation and characterization of three new anti-proliferative Sesquiterpenes from Polygonum barbatum and their mechanism via apoptotic pathway.NGF FLIPs TrkA onto the death TRAIL in neuroblastoma cells.Rapamycin, an mTOR inhibitor, induced apoptosis via independent mitochondrial and death receptor pathway in retinoblastoma Y79 cell.Aminoglucose-functionalized, redox-responsive polymer nanomicelles for overcoming chemoresistance in lung cancer cells.Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells.Nanoparticles for Immune Cytokine TRAIL-Based Cancer Therapy.Metformin sensitizes triple-negative breast cancer to proapoptotic TRAIL receptor agonists by suppressing XIAP expression.
P2860
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P2860
Targeting the extrinsic apoptotic pathway in cancer: lessons learned and future directions
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
Targeting the extrinsic apopto ...... learned and future directions
@en
type
label
Targeting the extrinsic apopto ...... learned and future directions
@en
prefLabel
Targeting the extrinsic apopto ...... learned and future directions
@en
P2860
P356
P1476
Targeting the extrinsic apopto ...... learned and future directions
@en
P2093
Avi Ashkenazi
P2860
P304
P356
10.1172/JCI80420
P407
P577
2015-02-02T00:00:00Z