Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis.
about
RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivoCpG island promoter methylation and silencing of 14-3-3sigma gene expression in LNCaP and Tramp-C1 prostate cancer cell lines is associated with methyl-CpG-binding protein MBD2DNA demethylation and invasive cancer: implications for therapeuticsPlasminogen Activator System and Breast Cancer: Potential Role in Therapy Decision Making and Precision MedicineOverexpression and hypomethylation of flap endonuclease 1 gene in breast and other cancersEpigenetic and antitumor effects of platinum(IV)-octanoato conjugates.The implications of DNA methylation for toxicology: toward toxicomethylomics, the toxicology of DNA methylationChromatin remodeling in mammary gland differentiation and breast tumorigenesis.Transcriptional regulation of hTREX84 in human cancer cells.Distinct functional patterns of gene promoter hypomethylation and hypermethylation in cancer genomesSynergistic effects of combined DNA methyltransferase inhibition and MBD2 depletion on breast cancer cells; MBD2 depletion blocks 5-aza-2'-deoxycytidine-triggered invasivenessProtease-activated receptors mediate crosstalk between coagulation and fibrinolysis.N6-methyladenosine modification in mRNA: machinery, function and implications for health and diseases.Methylated DNA binding domain protein 2 (MBD2) coordinately silences gene expression through activation of the microRNA hsa-mir-496 promoter in breast cancer cell lineCHST11 gene expression and DNA methylation in breast cancerInhibitory effect of ethanol extract of Ocimum sanctum on osteopontin mediated metastasis of NCI-H460 non-small cell lung cancer cells.S-adenosylmethionine blocks osteosarcoma cells proliferation and invasion in vitro and tumor metastasis in vivo: therapeutic and diagnostic clinical applicationsEpigenetic modulation of insulin-like growth factor-II overexpression by hepatitis B virus X protein in hepatocellular carcinoma.Demethylation-linked activation of urokinase plasminogen activator is involved in progression of prostate cancer.IRX1 hypomethylation promotes osteosarcoma metastasis via induction of CXCL14/NF-κB signaling.Prostaglandin E2 promotes intestinal tumor growth via DNA methylation.5-Aza-2'-deoxycytidine stress response and apoptosis in prostate cancer.PEGylated DX-1000: pharmacokinetics and antineoplastic activity of a specific plasmin inhibitor.Epigenetic silencing of Kruppel like factor-3 increases expression of pro-metastatic miR-182.Targeting epigenetic regulatory mechanisms in cancer chemoprevention.Prenatal synthetic glucocorticoid treatment changes DNA methylation states in male organ systems: multigenerational effects.Biologic characteristics of premalignant breast disease.DNA methylation signatures for breast cancer classification and prognosisSystematic Identification and Assessment of Therapeutic Targets for Breast Cancer Based on Genome-Wide RNA Interference TranscriptomesTherapeutic implications of DNA methylation.Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo.A common promoter hypomethylation signature in invasive breast, liver and prostate cancer cell lines reveals novel targets involved in cancer invasiveness.Epigenetic tête-à-tête: the bilateral relationship between chromatin modifications and DNA methylation.Radiation-induced hypomethylation triggers urokinase plasminogen activator transcription in meningioma cellsThe role of aberrant promoter hypermethylation of DACT1 in bladder urothelial carcinoma.The dynamic epigenome and its implications in toxicology.Stilbenoids remodel the DNA methylation patterns in breast cancer cells and inhibit oncogenic NOTCH signaling through epigenetic regulation of MAML2 transcriptional activity.Epigenomics and breast cancerMBD2 as a novel marker associated with poor survival of patients with hepatocellular carcinoma after hepatic resection.Rescue of Early bace-1 and Global DNA Demethylation by S-Adenosylmethionine Reduces Amyloid Pathology and Improves Cognition in an Alzheimer's Model
P2860
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P2860
Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Reversal of the hypomethylatio ...... cancer growth and metastasis.
@en
type
label
Reversal of the hypomethylatio ...... cancer growth and metastasis.
@en
prefLabel
Reversal of the hypomethylatio ...... cancer growth and metastasis.
@en
P2093
P2860
P356
P1476
Reversal of the hypomethylatio ...... cancer growth and metastasis.
@en
P2093
Moshe Szyf
Pouya Pakneshan
Shafaat A Rabbani
P2860
P304
31735-31744
P356
10.1074/JBC.M401669200
P407
P577
2004-05-18T00:00:00Z