Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels.
about
Build-ups in the supply chain of the brain: on the neuroenergetic cause of obesity and type 2 diabetes mellitusRegulation of glucose homeostasis by GLP-1Functional implications of limited leptin receptor and ghrelin receptor coexpression in the brainFrom observation to experimentation: leptin action in the mediobasal hypothalamusNicotinic receptor-mediated effects on appetite and food intakeNesfatin-1 inhibits NPY neurons in the arcuate nucleusMetabolic imprinting: critical impact of the perinatal environment on the regulation of energy homeostasisLeptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and KATP channel activationThe aminoguanidine carboxylate BVT.12777 activates ATP-sensitive K+ channels in the rat insulinoma cell line, CRI-G1From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behaviorGlucose sensing neurons in the ventromedial hypothalamusExpanding frontiers in weight-control research explored by young investigatorsDiacylglycerol kinase zeta in hypothalamus interacts with long form leptin receptor. Relation to dietary fat and body weight regulationAlternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neuronsDisruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulationMechanisms limiting body growth in mammalsHormone and glucose signalling in POMC and AgRP neurons.PI3K integrates the action of insulin and leptin on hypothalamic neurons.A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic beta-cells.Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice.The action of leptin in the ventral tegmental area to decrease food intake is dependent on Jak-2 signalingContributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death.Short photoperiod-induced decrease of histamine H3 receptors facilitates activation of hypothalamic neurons in the Siberian hamster.Divergent regulation of energy expenditure and hepatic glucose production by insulin receptor in agouti-related protein and POMC neuronsMetabolic characterization of a mouse deficient in all known leptin receptor isoforms.Alteration of the leptin network in late morbid obesity induced in mice by brain infection with canine distemper virusAntagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenalin.Neurobiology of food intake in health and disease.Leptin action in the forebrain regulates the hindbrain response to satiety signals.Glucose prevents the fall in ventromedial hypothalamic GABA that is required for full activation of glucose counterregulatory responses during hypoglycemiaDevelopmental switch of leptin signaling in arcuate nucleus neurons.Leptin: a multifunctional hormone.KATP channels gated by intracellular nucleotides and phospholipids.Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons.Leptin suppression of insulin secretion and gene expression in human pancreatic islets: implications for the development of adipogenic diabetes mellitus.Cellular defenses against excitotoxic insults.Modulation of olfactory sensitivity and glucose-sensing by the feeding state in obese Zucker ratsDifferential effects of hypothalamic long-chain fatty acid infusions on suppression of hepatic glucose production.Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3.Brain glucose-sensing mechanisms: ubiquitous silencing by aglycemia vs. hypothalamic neuroendocrine responses.
P2860
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P2860
Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels.
@en
type
label
Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels.
@en
prefLabel
Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels.
@en
P2093
P356
P1433
P1476
Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels
@en
P2093
P2888
P304
P356
10.1038/37379
P407
P577
1997-12-01T00:00:00Z
P6179
1013866954