Translational aspects of blood-brain barrier transport and central nervous system effects of drugs: from discovery to patients. - Wikidata - awgldk - TriplyDB

Translational aspects of blood-brain barrier transport and central nervous system effects of drugs: from discovery to patients.

Translational aspects of blood-brain barrier transport and central nervous system effects of drugs: from discovery to patients.

http://www.wikidata.org/entity/Q38351399

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Importance of Drug Pharmacokinetics at the Site of Action Pharmacokinetic Properties of Anticancer Agents for the Treatment of Central Nervous System Tumors: Update of the Literature.Atomoxetine: A Review of Its Pharmacokinetics and Pharmacogenomics Relative to Drug Disposition.Oral Targeted Therapies and Central Nervous System (CNS) Metastases.The pathophysiology of defective proteostasis in the hypothalamus - from obesity to ageing.A Generic Multi-Compartmental CNS Distribution Model Structure for 9 Drugs Allows Prediction of Human Brain Target Site Concentrations Novel CNS drug discovery and development approach: model-based integration to predict neuro-pharmacokinetics and pharmacodynamics.Lessons Learned from Alzheimer Disease: Clinical Trials with Negative Outcomes.Blood-brain barrier: an impediment to neuropharmaceuticals.Clinical Pharmacokinetics and Pharmacodynamics of Drugs in the Central Nervous System.Elimination of substances from the brain parenchyma: efflux via perivascular pathways and via the blood-brain barrier

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Translational aspects of blood-brain barrier transport and central nervous system effects of drugs: from discovery to patients.

http://www.wikidata.org/entity/Q38351399

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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2015年學術文章

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2015年學術文章

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Translational aspects of blood ...... s: from discovery to patients.

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Clinical Pharmacology & Therapeutics

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M Hammarlund-Udenaes

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Sequential cerebrospinal fluid and plasma sampling in humans: 24-hour melatonin measurements in normal subjects and after peripheral sympathectomy

Structure and function of the blood-brain barrier

Rational use of plasma protein and tissue binding data in drug design.

A role for fMRI in optimizing CNS drug development.

Considerations in the use of cerebrospinal fluid pharmacokinetics to predict brain target concentrations in the clinical setting: implications of the barriers between blood and brain.

Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.

Potential role of ABC transporters as a detoxification system at the blood-CSF barrier.

Species differences in blood-brain barrier transport of three positron emission tomography radioligands with emphasis on P-glycoprotein transport.

Fine structural localization of a blood-brain barrier to exogenous peroxidase

The use of microdialysis in CNS drug delivery studies. Pharmacokinetic perspectives and results with analgesics and antiepileptics.

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380-394

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10.1002/CPT.76

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blood–brain barrier