A novel tumor-targeted therapy using a claudin-4-targeting molecule.
about
Clostridium perfringens Enterotoxin: Action, Genetics, and Translational ApplicationsParadigms lost-an emerging role for over-expression of tight junction adhesion proteins in cancer pathogenesisChallenges associated with the targeted delivery of gelonin to claudin-expressing cancer cells with the use of activatable cell penetrating peptides to enhance potency.A novel screening system for claudin binder using baculoviral display.Transcriptional control of tight junction proteins via a protein kinase C signal pathway in human telomerase reverse transcriptase-transfected human pancreatic duct epithelial cells.Specificity of interaction between clostridium perfringens enterotoxin and claudin-family tight junction proteinsUse of Clostridium perfringens Enterotoxin and the Enterotoxin Receptor-Binding Domain (C-CPE) for Cancer Treatment: Opportunities and Challenges.Expression of claudins and their prognostic significance in noninvasive urothelial neoplasms of the human urinary bladder.Contrasting effects of ERK on tight junction integrity in differentiated and under-differentiated Caco-2 cell monolayersEpithelial-mesenchymal transition in ovarian carcinomaRapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapyEfficacy and safety evaluation of claudin-4-targeted antitumor therapy using a human and mouse cross-reactive monoclonal antibody.Biomarkers for Basal-like Breast Cancer.Proof of concept for claudin-targeted drug development.Targeting claudin-4 in human pancreatic cancer.Regulation of tight junctions in upper airway epithelium.Claudins and gastric carcinogenesis.Targeting tight junctions during epithelial to mesenchymal transition in human pancreatic cancer.Role of tight junctions in signal transduction: an update.The interaction of Clostridium perfringens enterotoxin with receptor claudins.Directed structural modification of Clostridium perfringens enterotoxin to enhance binding to claudin-5.Bacterial Toxins for Oncoleaking Suicidal Cancer Gene Therapy.Claudin-targeted drug development using anti-claudin monoclonal antibodies to treat hepatitis and cancer.Regulation of tight junctions in human normal pancreatic duct epithelial cells and cancer cells.Mechanism of Clostridium perfringens enterotoxin interaction with claudin-3/-4 protein suggests structural modifications of the toxin to target specific claudins.Novel Clostridium perfringens enterotoxin suicide gene therapy for selective treatment of claudin-3- and -4-overexpressing tumors.Tricellulin expression in normal and neoplastic human pancreas.
P2860
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P2860
A novel tumor-targeted therapy using a claudin-4-targeting molecule.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
A novel tumor-targeted therapy using a claudin-4-targeting molecule.
@en
type
label
A novel tumor-targeted therapy using a claudin-4-targeting molecule.
@en
prefLabel
A novel tumor-targeted therapy using a claudin-4-targeting molecule.
@en
P2093
P356
P1476
A novel tumor-targeted therapy using a claudin-4-targeting molecule.
@en
P2093
Hideki Kakutani
Kiyohito Yagi
Masuo Kondoh
Shin-Ichi Tsunoda
Takao Hamakubo
Yasuhiko Horiguchi
Yasuhiro Mochizuki
Yasuo Tsutsumi
P304
P356
10.1124/MOL.109.058412
P577
2009-07-28T00:00:00Z