The serine protease inhibitor protease nexin-1 controls mammary cancer metastasis through LRP-1-mediated MMP-9 expression.
about
LRP-1: a checkpoint for the extracellular matrix proteolysisThe Matricellular Receptor LRP1 Forms an Interface for Signaling and Endocytosis in Modulation of the Extracellular Tumor EnvironmentRoles of low-density lipoprotein receptor-related protein 1 in tumorsBiochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): the next decadeLDL receptor-related protein-1: a regulator of inflammation in atherosclerosis, cancer, and injury to the nervous systemAptamer-mediated impairment of EGFR-integrin αvβ3 complex inhibits vasculogenic mimicry and growth of triple-negative breast cancers.Low-Density Lipoprotein Receptor-Related Protein-1 Signaling in Angiogenesis.Brain metastasis-initiating cells: survival of the fittest.Low density lipoprotein receptor-related protein 1 (LRP1) forms a signaling complex with platelet-derived growth factor receptor-beta in endosomes and regulates activation of the MAPK pathwayLRP-1 promotes cancer cell invasion by supporting ERK and inhibiting JNK signaling pathwaysMatrix metalloproteinases in tumorigenesis: an evolving paradigm.The serine protease inhibitor serpinE2 is a novel target of ERK signaling involved in human colorectal tumorigenesisAcute lymphoid leukemia cells with greater stem cell antigen-1 (Ly6a/Sca-1) expression exhibit higher levels of metalloproteinase activity and are more aggressive in vivo.Spatiotemporal expression of SERPINE2 in the human placenta and its role in extravillous trophoblast migration and invasionExtracellular molecules involved in cancer cell invasionInhibition of cyclo-oxygenase 2 reduces tumor metastasis and inflammatory signaling during blockade of vascular endothelial growth factor.Serpine2/PN-1 Is Required for Proliferative Expansion of Pre-Neoplastic Lesions and Malignant Progression to Medulloblastoma.SERPINE2 Inhibits IL-1α-Induced MMP-13 Expression in Human Chondrocytes: Involvement of ERK/NF-κB/AP-1 Pathways.LRP-1--CD44, a new cell surface complex regulating tumor cell adhesion.A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis.Role of plasminogen activator inhibitor-1 in urokinase's paradoxical in vivo tumor suppressing or promoting effectsGenes regulated in metastatic osteosarcoma: evaluation by microarray analysis in four human and two mouse cell line systems.Silibinin and Paclitaxel Cotreatment Significantly Suppress the Activity and Lung Metastasis of Triple Negative 4T1 Mammary Tumor Cell in Mice.Serpin E2 promotes breast cancer metastasis by remodeling the tumor matrix and polarizing tumor associated macrophages.Exosomes and communication between tumours and the immune system: are all exosomes equal?The secretome signature of colon cancer cell lines.Inhibition of breast cancer metastasis by paclitaxel-loaded pH responsive poly(β-amino ester) copolymer micelles.Prognostic significance of SERPINE2 in gastric cancer and its biological function in SGC7901 cells.Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma.Regulation of the Extracellular SERPINA5 (Protein C Inhibitor) Penetration Through Cellular Membranes.Matrix metalloproteinase-9 regulates tumor cell invasion through cleavage of protease nexin-1Role of LRP-1 in cancer cell migration in 3-dimensional collagen matrix.Identification of Nucleobindin-2 as a Potential Biomarker for Breast Cancer Metastasis Using iTRAQ-based Quantitative Proteomic Analysis.A slow-cycling subpopulation of melanoma cells with highly invasive properties.Identification of LRP-1 as an endocytosis and recycling receptor for β1-integrin in thyroid cancer cells.The Kunitz Domain I of Hepatocyte Growth Factor Activator Inhibitor-2 Inhibits Matriptase Activity and Invasive Ability of Human Prostate Cancer Cells.ZEB1-repressed microRNAs inhibit autocrine signaling that promotes vascular mimicry of breast cancer cells.Proteomic analysis reveals a proteolytic feedback loop in murine seminal fluid.Cancer: An extravascular route for tumour cells.Expression pattern of human SERPINE2 in a variety of human tumors.
P2860
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P2860
The serine protease inhibitor protease nexin-1 controls mammary cancer metastasis through LRP-1-mediated MMP-9 expression.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
The serine protease inhibitor ...... P-1-mediated MMP-9 expression.
@en
type
label
The serine protease inhibitor ...... P-1-mediated MMP-9 expression.
@en
prefLabel
The serine protease inhibitor ...... P-1-mediated MMP-9 expression.
@en
P2093
P1433
P1476
The serine protease inhibitor ...... P-1-mediated MMP-9 expression.
@en
P2093
Bérengère Fayard
Denis Monard
Eliza Moreno
Fabrizio Bianchi
Julien Dey
Nancy E Hynes
Sabrina Djaffer
P304
P356
10.1158/0008-5472.CAN-08-4573
P407
P577
2009-07-07T00:00:00Z