Functional characterization of three single-nucleotide polymorphisms present in the human APOE promoter sequence: Differential effects in neuronal cells and on DNA-protein interactions.
about
Impact of apolipoprotein E on Alzheimer's diseasePuF, an antimetastatic and developmental signaling protein, interacts with the Alzheimer's amyloid-β precursor protein via a tissue-specific proximal regulatory element (PRE)Gata5 deficiency causes airway constrictor hyperresponsiveness in mice.A functional mutation at position -155 in porcine APOE promoter affects gene expression.Discovery of Novel Human Gene Regulatory Modules from Gene Co-expression and Promoter Motif Analysis.APOE genotype-function relationship: evidence of -491 A/T promoter polymorphism modifying transcription control but not type 2 diabetes riskCognitive changes preceding clinical symptom onset of mild cognitive impairment and relationship to ApoE genotype.Gene × environment interaction by a longitudinal epigenome-wide association study (LEWAS) overcomes limitations of genome-wide association study (GWAS)Structural and functional characterization of H2 haplotype MAPT promoter: unique neurospecific domains and a hypoxia-inducible element would enhance rationally targeted tauopathy research for Alzheimer's disease.Daidzein Augments Cholesterol Homeostasis via ApoE to Promote Functional Recovery in Chronic StrokeGenome-wide pathway analysis of memory impairment in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort implicates gene candidates, canonical pathways, and networks.Pathways to neurodegeneration: mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disordersSignificance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis.Is there a significant interaction effect between apolipoprotein E rs405509 T/T and ε4 genotypes on cognitive impairment and gray matter volume?The "LEARn" (Latent Early-life Associated Regulation) model integrates environmental risk factors and the developmental basis of Alzheimer's disease, and proposes remedial steps.Association between polymorphisms in the promoter region of the apolipoprotein E (APOE) gene and Alzheimer's disease: A meta-analysis.Effects of molecular hydrogen assessed by an animal model and a randomized clinical study on mild cognitive impairment.Disrupted Brain Structural Connectivity: Pathological Interactions Between Genetic APOE ε4 Status and Developed MCI Condition.
P2860
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P2860
Functional characterization of three single-nucleotide polymorphisms present in the human APOE promoter sequence: Differential effects in neuronal cells and on DNA-protein interactions.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Functional characterization of ...... d on DNA-protein interactions.
@en
type
label
Functional characterization of ...... d on DNA-protein interactions.
@en
prefLabel
Functional characterization of ...... d on DNA-protein interactions.
@en
P2093
P2860
P50
P356
P1476
Functional characterization of ...... d on DNA-protein interactions.
@en
P2093
Debomoy K Lahiri
Jack T Rogers
Yuan-Wen Ge
P2860
P304
P356
10.1002/AJMG.B.30973
P577
2010-01-01T00:00:00Z