Modular structure of glucocorticoid receptor domains is not equivalent to functional independence. Stability and activity of the steroid binding domain are controlled by sequences in separate domains.

Modular structure of glucocorticoid receptor domains is not equivalent to functional independence. Stability and activity of the steroid binding domain are controlled by sequences in separate domains.

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http://www.wikidata.org/entity/Q38353748
The proper folding of a long C-terminal segment of the yeast Lys14p regulator is required for activation of LYS genes in response to the metabolic effector.Identification of glucocorticoid receptor domains involved in transrepression of transforming growth factor-beta actionMutations at positions 547-553 of rat glucocorticoid receptors reveal that hsp90 binding requires the presence, but not defined composition, of a seven-amino acid sequence at the amino terminus of the ligand binding domainDiscrimination between NL1- and NL2-mediated nuclear localization of the glucocorticoid receptorEffects of parabens on adipocyte differentiation.Mutations flanking the polyglutamine repeat in the modulatory domain of rat glucocorticoid receptor lead to an increase in affinity for hormone.Binding of hsp90 to the glucocorticoid receptor requires a specific 7-amino acid sequence at the amino terminus of the hormone-binding domain.Transactivation specificity of glucocorticoid versus progesterone receptors. Role of functionally different interactions of transcription factors with amino- and carboxyl-terminal receptor domains.Asymmetric catalytic ene-cyclization approach to 2-fluoro-19-nor-1,25-dihydroxyvitamin D(3) A-ring analog with significant transactivation activity.The antibiotic rifampicin is a nonsteroidal ligand and activator of the human glucocorticoid receptor.Steroid-induced conformational changes at ends of the hormone-binding domain in the rat glucocorticoid receptor are independent of agonist versus antagonist activity.
P2860

Modular structure of glucocorticoid receptor domains is not equivalent to functional independence. Stability and activity of the steroid binding domain are controlled by sequences in separate domains.

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http://www.wikidata.org/entity/Q38353748
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1996 nî lūn-bûn
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1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
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1996年學術文章
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name
Modular structure of glucocort ...... sequences in separate domains.
@en
type
label
Modular structure of glucocort ...... sequences in separate domains.
@en
prefLabel
Modular structure of glucocort ...... sequences in separate domains.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Modular structure of glucocort ...... sequences in separate domains
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698