PU.1 (Spi-1) and C/EBP alpha regulate the granulocyte colony-stimulating factor receptor promoter in myeloid cells.
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Interleukin (IL)-32β-mediated CCAAT/enhancer-binding protein α (C/EBPα) phosphorylation by protein kinase Cδ (PKCδ) abrogates the inhibitory effect of C/EBPα on IL-10 productionHOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cellsHOXA9 regulates miR-155 in hematopoietic cellsNegative cross-talk between hematopoietic regulators: GATA proteins repress PU.1Neutrophil-specific granule deficiency results from a novel mutation with loss of function of the transcription factor CCAAT/enhancer binding protein epsilonCCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicingTwist-2 controls myeloid lineage development and functionAn essential role for C/EBPbeta in female reproductionId2 intrinsically regulates lymphoid and erythroid development via interaction with different target proteinsC/EBP and DEK coordinately regulate myeloid differentiationSumoylation of CCAAT/enhancer-binding protein α is implicated in hematopoietic stem/progenitor cell development through regulating runx1 in zebrafish.Integrating extrinsic and intrinsic cues into a minimal model of lineage commitment for hematopoietic progenitors.Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.Potential autoregulation of transcription factor PU.1 by an upstream regulatory elementIn vivo deficiency of both C/EBPβ and C/EBPε results in highly defective myeloid differentiation and lack of cytokine response.Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitorsCCAAT/enhancer binding protein epsilon is a potential retinoid target gene in acute promyelocytic leukemia treatment.Regulation of eosinophil-specific gene expression by a C/EBP-Ets complex and GATA-1.PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors.Hoxa9 immortalizes a granulocyte-macrophage colony-stimulating factor-dependent promyelocyte capable of biphenotypic differentiation to neutrophils or macrophages, independent of enforced meis expression.c-Myc is a critical target for c/EBPalpha in granulopoiesis.Dichotomy of AML1-ETO functions: growth arrest versus block of differentiationDecreased neutrophil apoptosis in quiescent ANCA-associated systemic vasculitis.STAT3 controls myeloid progenitor growth during emergency granulopoiesis.RUNX1 regulates corepressor interactions of PU.1.Granulopoiesis requires increased C/EBPα compared to monopoiesis, correlated with elevated Cebpa in immature G-CSF receptor versus M-CSF receptor expressing cells.Identification of Flt3⁺CD150⁻ myeloid progenitors in adult mouse bone marrow that harbor T lymphoid developmental potential.Synergistic induction of galectin-1 by CCAAT/enhancer binding protein alpha and hypoxia-inducible factor 1alpha and its role in differentiation of acute myeloid leukemic cells.The +37 kb Cebpa Enhancer Is Critical for Cebpa Myeloid Gene Expression and Contains Functional Sites that Bind SCL, GATA2, C/EBPα, PU.1, and Additional Ets Factors.C/EBPalpha determines hematopoietic cell fate in multipotential progenitor cells by inhibiting erythroid differentiation and inducing myeloid differentiationHigh levels of the BCR/ABL oncoprotein are required for the MAPK-hnRNP-E2 dependent suppression of C/EBPalpha-driven myeloid differentiationTargeted disruption of the PU.1 gene results in multiple hematopoietic abnormalitiesAbsence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient miceThe homeobox gene DLX4 regulates erythro-megakaryocytic differentiation by stimulating IL-1β and NF-κB signalingOverexpression of TRIB2 in human lung cancers contributes to tumorigenesis through downregulation of C/EBPαA Cell-Based High-Throughput Screening for Inducers of Myeloid Differentiation.Phosphorylation of C/EBPalpha inhibits granulopoiesis.Upregulation of interleukin 6 and granulocyte colony-stimulating factor receptors by transcription factor CCAAT enhancer binding protein alpha (C/EBP alpha) is critical for granulopoiesisGenome-scale definition of the transcriptional programme associated with compromised PU.1 activity in acute myeloid leukaemia.
P2860
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P2860
PU.1 (Spi-1) and C/EBP alpha regulate the granulocyte colony-stimulating factor receptor promoter in myeloid cells.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
PU.1 (Spi-1) and C/EBP alpha r ...... tor promoter in myeloid cells.
@en
type
label
PU.1 (Spi-1) and C/EBP alpha r ...... tor promoter in myeloid cells.
@en
prefLabel
PU.1 (Spi-1) and C/EBP alpha r ...... tor promoter in myeloid cells.
@en
P2093
P1433
P1476
PU.1 (Spi-1) and C/EBP alpha r ...... ptor promoter in myeloid cells
@en
P2093
P304
P407
P577
1996-08-01T00:00:00Z