Extending the understanding of mutagenicity: structural insights into primer-extension past a benzo[a]pyrene diol epoxide-DNA adduct.

Extending the understanding of mutagenicity: structural insights into primer-extension past a benzo[a]pyrene diol epoxide-DNA adduct.

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http://www.wikidata.org/entity/Q38356442
3′-Intercalation of a N 2 -dG 1 R - trans - anti -Benzo[ c ]phenanthrene DNA Adduct in an Iterated (CG) 3 RepeatThe N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesionsInhibition of Werner syndrome helicase activity by benzo[a]pyrene diol epoxide adducts can be overcome by replication protein A.Crystal and molecular structure of a benzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct: absolute configuration and conformationStereochemistry and position-dependent effects of carcinogens on TATA/TBP binding.Effect of oxidatively damaged DNA on the active site preorganization during nucleotide incorporation in a high fidelity polymerase from Bacillus stearothermophilus.Nucleotide incorporation by human DNA polymerase gamma opposite benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyguanosine and deoxyadenosine.Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis.The spacious active site of a Y-family DNA polymerase facilitates promiscuous nucleotide incorporation opposite a bulky carcinogen-DNA adduct: elucidating the structure-function relationship through experimental and computational approaches.RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications.Following an environmental carcinogen N2-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase.Increased flexibility enhances misincorporation: temperature effects on nucleotide incorporation opposite a bulky carcinogen-DNA adduct by a Y-family DNA polymerase.Structure of a high fidelity DNA polymerase bound to a benzo[a]pyrene adduct that blocks replication.Active Site Interactions Impact Phosphoryl Transfer during Replication of Damaged and Undamaged DNA by Escherichia coli DNA Polymerase I.Mutagenic Replication of N2-Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase I and Sulfolobus solfataricus DNA Polymerase IV.Genotoxicity risk assessment of diversely substituted quinolines using the SOS chromotest.
P2860

Extending the understanding of mutagenicity: structural insights into primer-extension past a benzo[a]pyrene diol epoxide-DNA adduct.

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http://www.wikidata.org/entity/Q38356442
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2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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name
Extending the understanding of ...... yrene diol epoxide-DNA adduct.
@en
type
label
Extending the understanding of ...... yrene diol epoxide-DNA adduct.
@en
prefLabel
Extending the understanding of ...... yrene diol epoxide-DNA adduct.
@en
P1433
P1476
P2093
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P1433
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Extending the understanding of ...... yrene diol epoxide-DNA adduct.
@en
P2093
P304
P31
P356
10.1016/S0022-2836(03)00187-6
P407
P433
P478
P577
P698