Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells.
about
Pathophysiological implications of neurovascular P450 in brain disordersBlood-brain barrier integrity and glial support: mechanisms that can be targeted for novel therapeutic approaches in strokeDrug-induced trafficking of p-glycoprotein in human brain capillary endothelial cells as demonstrated by exposure to mitomycin CTranscriptional control of the multi-drug transporter ABCB1 by transcription factor Sp3 in different human tissuesA multi-system approach assessing the interaction of anticonvulsants with P-gpA novel blood-brain barrier co-culture system for drug targeting of Alzheimer's disease: establishment by using acitretin as a model drugTriggering of protection mechanism against Phoneutria nigriventer spider venom in the brainInduction of P-glycoprotein and Bcrp at the rat blood-brain barrier following a subchronic morphine treatment is mediated through NMDA/COX-2 activationQuantitative targeted proteomics for membrane transporter proteins: method and application.Significance of lipid composition in a blood-brain barrier-mimetic PAMPA assay.Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's diseaseABC and SLC transporter expression and proton oligopeptide transporter (POT) mediated permeation across the human blood--brain barrier cell line, hCMEC/D3 [corrected]2,3,7,8-Tetrachlorodibenzo-p-dioxin induced cell-specific drug transporters with acquired cisplatin resistance in cisplatin sensitive cancer cells.Aryl hydrocarbon receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier.Targeting the neurovascular unit for treatment of neurological disorders.A new nonpolar N-hydroxy imidazoline lead compound with improved activity in a murine model of late-stage Trypanosoma brucei brucei infection is not cross-resistant with diamidines.Oxcarbazepine-loaded polymeric nanoparticles: development and permeability studies across in vitro models of the blood-brain barrier and human placental trophoblast.Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvesselsEffect of status epilepticus and antiepileptic drugs on CYP2E1 brain expressionSertraline-induced potentiation of the CYP3A4-dependent neurotoxicity of carbamazepine: an in vitro study.Altered glycaemia differentially modulates efflux transporter expression and activity in hCMEC/D3 cell line.Targeting blood-brain barrier changes during inflammatory pain: an opportunity for optimizing CNS drug delivery.Inflammatory cell trafficking across the blood-brain barrier: chemokine regulation and in vitro models.In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice.Pharmacophore-based discovery of inhibitors of a novel drug/proton antiporter in human brain endothelial hCMEC/D3 cell lineATP-binding cassette transporters in immortalised human brain microvascular endothelial cells in normal and hypoxic conditionsModeling the blood-brain barrier using stem cell sources.Targeted drug delivery to treat pain and cerebral hypoxiaNanoparticle transport across the blood brain barrier.Induction of acquired drug resistance in endothelial cells and its involvement in anticancer therapy.Developmental changes in the transcriptome of the rat choroid plexus in relation to neuroprotectionCYP3A5*3 and C3435T MDR1 polymorphisms in prognostication of drug-resistant epilepsy in children and adolescentsExpression and functional relevance of UGT1A4 in a cohort of human drug-resistant epileptic brains.Drug interactions at the blood-brain barrier: fact or fantasy?Immortalized human brain endothelial cell line HCMEC/D3 as a model of the blood-brain barrier facilitates in vitro studies of central nervous system infection by Cryptococcus neoformans.Interactions of dietary phytochemicals with ABC transporters: possible implications for drug disposition and multidrug resistance in cancer.ABC transporters and cytochromes P450 in the human central nervous system: influence on brain pharmacokinetics and contribution to neurodegenerative disorders.Blood-brain barrier P450 enzymes and multidrug transporters in drug resistance: a synergistic role in neurological diseases.Nanostructure-based drug delivery systems for brain targeting.The hCMEC/D3 cell line as a model of the human blood brain barrier.
P2860
Q26745632-9C133DC4-D78B-47C9-821C-FA4AD249845BQ26864317-D0AD5B91-790D-4B27-B332-042E6590681DQ27323067-AB81A867-6C34-406A-A69A-30840CCA03E9Q28484634-1AEAFFBC-0F96-48A0-9B95-9E4732155577Q28533527-AB8B3C88-E007-4789-AA85-004B4C4EE732Q28540639-F172ABD0-A49F-4C91-BA50-63D1C2D71C75Q28542941-BB5EA2E7-2D3C-431D-B1E1-C2683BEF7ED5Q28578377-57850ED5-E4D4-4213-B89C-2768A852E56AQ33803962-E17D75EF-0B17-4E82-9E9A-060D343E01AAQ33834662-152A3D40-F7D3-4A9D-87CF-F958CCCE3926Q33862071-1A1E887C-A312-4F5D-A22D-DFE0F14AF0FEQ34036791-43FE8CC1-FFA4-4CFA-93C7-2159626E05DFQ34208237-79BC4C89-F042-4478-BF2E-B161ACA56CAAQ34502705-2EC53130-D996-4495-BF78-0E07BAAEB37DQ34974827-F61DDB6D-4005-4FB4-B8D6-2C5DC7D8C42CQ35105995-4122E5E9-C8AA-4B32-9957-2B1FC281ED87Q35185771-5C00B078-0D1C-4B57-8F59-1C9ECBB3F97BQ35232729-3E1328C4-E402-4724-84D9-14295AFF45FDQ35252029-849D095C-AF41-421C-9B3A-267A48EED120Q35551134-B96F1E6B-E732-43F7-BFC0-53F2AFEC5661Q35685226-40E0E1DF-1F21-48DB-BF8E-ED773C847A22Q35855634-B112AA42-F4B3-4FB1-976D-2F22BB6B2E83Q36059965-4202C03F-B49D-4F0C-977E-25B9EB2E2583Q36186153-6EC84A64-9CC2-4BF3-A497-DE1B6135196DQ36211219-500F8C77-450B-405F-B115-52C5872E9E1EQ36303213-9F881648-5C70-47C3-9F63-4AD808282509Q36588683-B904058F-ABD8-4F3C-B252-A4A956F8825BQ36591611-12D1CF44-A530-475E-B96B-0ADB064A6CB7Q36812347-F383DCB4-7BDF-4E37-AF45-C5E225E9D9E8Q37028731-ADB10642-3AAF-4DA5-A6F0-1D8413BAF100Q37079343-79FE9D65-0B98-45AF-BA47-506D20A4C130Q37104987-63D51954-4378-4784-8282-F3000CD1D622Q37249054-513BC6AC-AF2F-447A-9E9A-033AC7114208Q37362486-6ED896E5-B369-4914-A056-7A69C4071C44Q37410097-89765544-E646-4522-B240-92BFC60A69F1Q37740126-46D14DE1-59E7-4D35-A558-E43EC77996BCQ37789041-714313D4-F888-4834-9458-6094C3050A1BQ37875183-434962C0-A60D-4086-8D34-283E8FFAE317Q37939942-AA59680D-3CB9-4580-958E-298DFDE5D11DQ38093329-31F4E011-3879-4A68-A40C-108F91B64407
P2860
Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Expression and transcriptional ...... crovascular endothelial cells.
@en
type
label
Expression and transcriptional ...... crovascular endothelial cells.
@en
prefLabel
Expression and transcriptional ...... crovascular endothelial cells.
@en
P2093
P50
P1476
Expression and transcriptional ...... icrovascular endothelial cells
@en
P2093
Babette Weksler
Florence Miller
Pierre-Olivier Couraud
Richard J Weaver
Sandrine Dauchy
P304
P356
10.1016/J.BCP.2008.11.001
P407
P577
2008-11-12T00:00:00Z