The heat shock protein 90 inhibitor IPI-504 induces apoptosis of AKT-dependent diffuse large B-cell lymphomas.
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MEK Inhibition Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia (B-ALL) Cells to Dexamethasone through Modulation of mTOR Activity and Stimulation of AutophagyA purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas.BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapyHsp90 (heat shock protein 90) inhibitor occupancy is a direct determinant of client protein degradation and tumor growth arrest in vivoGenetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibitionInhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline.Therapy of newly diagnosed follicular lymphoma.A multicenter trial evaluating retaspimycin HCL (IPI-504) plus trastuzumab in patients with advanced or metastatic HER2-positive breast cancer.Retaspimycin hydrochloride (IPI-504): a novel heat shock protein inhibitor as an anticancer agent.Novel therapeutic targets for multiple myeloma.Hsp90 as a gatekeeper of tumor angiogenesis: clinical promise and potential pitfalls.Heat shock protein 90 and role of its chemical inhibitors in treatment of hematologic malignanciesEssential role of TAK1 in regulating mantle cell lymphoma survival.HSP90 inhibition by 17-DMAG reduces inflammation in J774 macrophages through suppression of Akt and nuclear factor-κB pathways.Virtual prototyping study shows increased ATPase activity of Hsp90 to be the key determinant of cancer phenotype.Multikinase inhibitor sorafenib exerts cytocidal efficacy against Non-Hodgkin lymphomas associated with inhibition of MAPK14 and AKT phosphorylation.Construction and in vitro/in vivo evaluation of 17-allylamino-17-demethoxygeldanamycin (17AAG)-loaded PEGylated nanostructured lipid carriers.
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P2860
The heat shock protein 90 inhibitor IPI-504 induces apoptosis of AKT-dependent diffuse large B-cell lymphomas.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
The heat shock protein 90 inhi ...... iffuse large B-cell lymphomas.
@en
type
label
The heat shock protein 90 inhi ...... iffuse large B-cell lymphomas.
@en
prefLabel
The heat shock protein 90 inhi ...... iffuse large B-cell lymphomas.
@en
P2093
P2860
P1476
The heat shock protein 90 inhi ...... diffuse large B-cell lymphomas
@en
P2093
Donna Neuberg
Hidenobu Takahashi
Jeffery L Kutok
Kunihiko Takeyama
Margaret A Shipp
P2860
P304
P356
10.1111/J.1365-2141.2008.07484.X
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P577
2008-11-13T00:00:00Z