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The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis.Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signallingPtk7 and Mcc, Unfancied Components in Non-Canonical Wnt Signaling and CancerThe kidney and planar cell polarity.Planar cell polarity signaling pathway in congenital heart diseasesXenopus Pkdcc1 and Pkdcc2 Are Two New Tyrosine Kinases Involved in the Regulation of JNK Dependent Wnt/PCP Signaling PathwayThe PTK7-related transmembrane proteins off-track and off-track 2 are co-receptors for Drosophila Wnt2 required for male fertilityA PTK7/Ror2 Co-Receptor Complex Affects Xenopus Neural Crest MigrationThe novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear.PTK7-Src signaling at epithelial cell contacts mediates spatial organization of actomyosin and planar cell polarity.PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium.PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation.Protein-tyrosine pseudokinase 7 (PTK7) directs cancer cell motility and metastasis.A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinomaPleiotRHOpic: Rho pathways are essential for all stages of Neural Crest development.Dissection of Xenopus laevis neural crest for in vitro explant culture or in vivo transplantationProtein tyrosine kinase 7 (PTK7) as a predictor of lymph node metastases and a novel prognostic biomarker in patients with prostate cancer.ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease.Vangl-dependent planar cell polarity signalling is not required for neural crest migration in mammals.Mechanism of Xenopus cranial neural crest cell migration.PTK7 marks the first human developmental EMT in vitro.Regulation of cell adhesions and motility during initiation of neural crest migrationExpression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis.Potential relation of aberrant proteolysis of human protein tyrosine kinase 7 (PTK7) chuzhoi by membrane type 1 matrix metalloproteinase (MT1-MMP) to congenital defects.Overexpression of the Promigratory and Prometastatic PTK7 Receptor Is Associated with an Adverse Clinical Outcome in Colorectal CancerCell polarity: The missing link in skeletal morphogenesis?Planar cell polarity signaling in craniofacial development.PTK7 regulates Id1 expression in CD44-high glioma cells.PTK7+ Mononuclear Cells Express VEGFR2 and Contribute to Vascular Stabilization by Upregulating Angiopoietin-1.The cytosolic domain of protein-tyrosine kinase 7 (PTK7), generated from sequential cleavage by a disintegrin and metalloprotease 17 (ADAM17) and γ-secretase, enhances cell proliferation and migration in colon cancer cellsPTK7: a new biomarker for immunophenotypic characterization of maturing T cells and T cell acute lymphoblastic leukemiaThe PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway.Insights into ectodomain shedding and processing of protein-tyrosine pseudokinase 7 (PTK7)Mouse models for dissecting vertebrate planar cell polarity signaling in the inner ear.Planar cell polarity signaling: the developing cell's compass.PTK 7 is a transforming gene and prognostic marker for breast cancer and nodal metastasis involvement.Mechanisms driving neural crest induction and migration in the zebrafish and Xenopus laevisThe planar cell polarity pathway in vertebrate development.Wnt5a: its signalling, functions and implication in diseases.Principles of planar polarity in animal development
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
PTK7 recruits dsh to regulate neural crest migration.
@en
type
label
PTK7 recruits dsh to regulate neural crest migration.
@en
prefLabel
PTK7 recruits dsh to regulate neural crest migration.
@en
P356
P1433
P1476
PTK7 recruits dsh to regulate neural crest migration.
@en
P2093
Annette Borchers
Iryna Shnitsar
P304
P356
10.1242/DEV.023556
P407
P577
2008-11-12T00:00:00Z