Expression of the transcription factor, Spi-1 (PU.1), in differentiating murine erythroleukemia cells Is regulated post-transcriptionally. Evidence for differential stability of transcription factor mRNAs following inducer exposure.

Expression of the transcription factor, Spi-1 (PU.1), in differentiating murine erythroleukemia cells Is regulated post-transcriptionally. Evidence for differential stability of transcription factor mRNAs following inducer exposure.

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http://www.wikidata.org/entity/Q38361520
The conserved 5'-untranslated leader of Spi-1 (PU.1) mRNA is highly structured and potently inhibits translation in vitro but not in vivoSpi-1/PU.1 is a positive regulator of the Fli-1 gene involved in inhibition of erythroid differentiation in friend erythroleukemic cell linesMaking (anti)sense of non-coding sequence conservationReduced PU.1 expression causes myeloid progenitor expansion and increased leukemia penetrance in mice expressing PML-RARalpha.Transcription factor Spi-B binds unique sequences present in the tandem repeat promoter/enhancer of JC virus and supports viral activitySox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia.C/EBPalpha determines hematopoietic cell fate in multipotential progenitor cells by inhibiting erythroid differentiation and inducing myeloid differentiationSpi-1 and Fli-1 directly activate common target genes involved in ribosome biogenesis in Friend erythroleukemic cells.The carboxyl-terminal domain of the granulocyte colony-stimulating factor receptor uncouples ribosomal biogenesis from cell cycle progression in differentiating 32D myeloid cells.Role of PU.1 in hematopoiesis.Inducers of erythroleukemic differentiation cause messenger RNAs that lack poly(A)-binding protein to accumulate in translationally inactive, salt-labile 80 S ribosomal complexes.
P2860

Expression of the transcription factor, Spi-1 (PU.1), in differentiating murine erythroleukemia cells Is regulated post-transcriptionally. Evidence for differential stability of transcription factor mRNAs following inducer exposure.

Item
http://www.wikidata.org/entity/Q38361520
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1996 nî lūn-bûn
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1996年の論文
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Expression of the transcriptio ...... As following inducer exposure.
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Expression of the transcriptio ...... As following inducer exposure.
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Expression of the transcriptio ...... As following inducer exposure.
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P1433
P1476
P2093
P2860
P304
P31
P356
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P577
P5875
P698
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P1433
P1476
Expression of the transcriptio ...... As following inducer exposure.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698