Acetyltransfer precedes uridylyltransfer in the formation of UDP-N-acetylglucosamine in separable active sites of the bifunctional GlmU protein of Escherichia coli.
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Crystal structure of Streptococcus pneumoniae N-acetylglucosamine-1-phosphate uridyltransferase bound to acetyl-coenzyme A reveals a novel active site architectureStructure of theE. colibifunctional GlmU acetyltransferase active site with substrates and productsGlucose-6-phosphate as a probe for the glucosamine-6-phosphate N-acetyltransferase Michaelis complexCharacterization of substrate binding and catalysis in the potential antibacterial targetN-acetylglucosamine-1-phosphate uridyltransferase (GlmU)Structure of a small-molecule inhibitor complexed with GlmU from Haemophilus influenzae reveals an allosteric binding siteStructural and biochemical characterization of a trapped coenzyme A adduct ofCaenorhabditis elegansglucosamine-6-phosphateN-acetyltransferase 1In Vitro Validation of Acetyltransferase Activity of GlmU as an Antibacterial Target in Haemophilus influenzaeAn aminoquinazoline inhibitor of the essential bacterial cell wall synthetic enzyme GlmU has a unique non-protein-kinase-like binding modeSaccharomyces cerevisiae GNA1, an essential gene encoding a novel acetyltransferase involved in UDP-N-acetylglucosamine synthesis.Kinetic analysis of the catalytic mechanism of serotonin N-acetyltransferase (EC 2.3.1.87)Kinetic modelling of GlmU reactions - prioritization of reaction for therapeutic applicationEvidence that WbpD is an N-acetyltransferase belonging to the hexapeptide acyltransferase superfamily and an important protein for O-antigen biosynthesis in Pseudomonas aeruginosa PAO1Kinetic and physical characterization of the inducible UDP-N-acetylglucosamine pyrophosphorylase from Giardia intestinalis.Phosphoribosyl Diphosphate (PRPP): Biosynthesis, Enzymology, Utilization, and Metabolic Significance.Streptococcus gordonii utilizes several distinct gene functions to recruit Porphyromonas gingivalis into a mixed community.High-throughput screening identifies novel inhibitors of the acetyltransferase activity of Escherichia coli GlmU.Probing the role of cysteine residues in glucosamine-1-phosphate acetyltransferase activity of the bifunctional GlmU protein from Escherichia coli: site-directed mutagenesis and characterization of the mutant enzymes.Identification of novel acetyltransferase activity on the thermostable protein ST0452 from Sulfolobus tokodaii strain 7.The bacterial cell wall as a source of antibacterial targets.RNA-binding proteins that inhibit RNA virus infection.Depletion of M. tuberculosis GlmU from Infected Murine Lungs Effects the Clearance of the Pathogen.Identification and characterization of novel small molecule inhibitors of the acetyltransferase activity of Escherichia coli N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU).Two bifunctional enzymes with ferric reduction ability play complementary roles during magnetosome synthesis in Magnetospirillum gryphiswaldense MSR-1.Cytoplasmic steps of peptidoglycan biosynthesis.Increasing the Thermostable Sugar-1-Phosphate Nucleotidylyltransferase Activities of the Archaeal ST0452 Protein through Site Saturation Mutagenesis of the 97th Amino Acid Position.Peptidoglycan biosynthesis machinery: a rich source of drug targets.Purification and biochemical characterisation of GlmU from Yersinia pestis.Characterization of the amino acid residues mediating the unique amino-sugar-1-phosphate acetyltransferase activity of the archaeal ST0452 protein.Wholly Rickettsia! Reconstructed Metabolic Profile of the Quintessential Bacterial Parasite of Eukaryotic Cells.Expression, purification and preliminary crystallographic analysis of N-acetylglucosamine-1-phosphate uridylyltransferase from Mycobacterium tuberculosis.Self-association studies of the bifunctional N-acetylglucosamine-1-phosphate uridyltransferase from Escherichia coliKinetic and inhibition studies on substrate channelling in the bifunctional enzyme catalysing C-terminal amidationAbsence of substrate channeling between active sites in the Agrobacterium tumefaciens IspDF and IspE enzymes of the methyl erythritol phosphate pathway.Biosynthesis of a novel 3-deoxy-D-manno-oct-2-ulosonic acid-containing outer core oligosaccharide in the lipopolysaccharide of Klebsiella pneumoniae.Dissection of the bifunctional Escherichia coli N-acetylglucosamine-1-phosphate uridyltransferase enzyme into autonomously functional domains and evidence that trimerization is absolutely required for glucosamine-1-phosphate acetyltransferase activiCj1123c (PglD), a multifaceted acetyltransferase from Campylobacter jejuni.In vivo and in vitro analyses of single-amino acid variants of the Salmonella enterica phosphotransacetylase enzyme provide insights into the function of its N-terminal domain.The Mechanism of Acetyl Transfer Catalyzed by Mycobacterium tuberculosis GlmU.Inhibition studies on Mycobacterium tuberculosis N-acetylglucosamine-1-phosphate uridyltransferase (GlmU).
P2860
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P2860
Acetyltransfer precedes uridylyltransfer in the formation of UDP-N-acetylglucosamine in separable active sites of the bifunctional GlmU protein of Escherichia coli.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Acetyltransfer precedes uridyl ...... U protein of Escherichia coli.
@en
type
label
Acetyltransfer precedes uridyl ...... U protein of Escherichia coli.
@en
prefLabel
Acetyltransfer precedes uridyl ...... U protein of Escherichia coli.
@en
P2093
P356
P1433
P1476
Acetyltransfer precedes uridyl ...... U protein of Escherichia coli.
@en
P2093
P304
P356
10.1021/BI952275A
P407
P577
1996-01-01T00:00:00Z