The GTPase Rem2 regulates synapse development and dendritic morphology
about
Molecular mechanisms of activity-dependent changes in dendritic morphology: role of RGK proteinsActivity-dependent subcellular cotrafficking of the small GTPase Rem2 and Ca2+/CaM-dependent protein kinase IIαAccelerated actin filament polymerization from microtubule plus ends.A loss-of-function analysis reveals that endogenous Rem2 promotes functional glutamatergic synapse formation and restricts dendritic complexityAncient origins of RGK protein function: modulation of voltage-gated calcium channels preceded the protostome and deuterostome split.Rem2-targeted shRNAs reduce frequency of miniature excitatory postsynaptic currents without altering voltage-gated Ca²⁺ currents.Emerging themes in GABAergic synapse developmentIsolation and molecular characterization of Rem2 isoforms in the rainbow trout (Oncorhynchus mykiss): Tissue and central nervous system expressionRem2, a member of the RGK family of small GTPases, is enriched in nuclei of the basal ganglia.CaMKII-dependent phosphorylation of the GTPase Rem2 is required to restrict dendritic complexity.Rem2 is an activity-dependent negative regulator of dendritic complexity in vivo.Rem2 in the bullfrog (Rana catesbeiana): Patterns of expression within the central nervous system and brain expression at different ontogenetic stagesRegulation of voltage-dependent calcium channels by RGK proteins.Dendritic spines: the locus of structural and functional plasticity.Activation of Dopamine D1 Receptors Regulates Dendritic Morphogenesis Through Rac1 and RhoA in Prefrontal Cortex Neurons.Localization of rem2 in the central nervous system of the adult rainbow trout (Oncorhynchus mykiss).TDP-43 misexpression causes defects in dendritic growth.Rem2 signaling affects neuronal structure and function in part by regulation of gene expression.Rem2 stabilizes intrinsic excitability and spontaneous firing in visual circuits.Neural architecture: from cells to circuits
P2860
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P2860
The GTPase Rem2 regulates synapse development and dendritic morphology
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
The GTPase Rem2 regulates synapse development and dendritic morphology
@en
type
label
The GTPase Rem2 regulates synapse development and dendritic morphology
@en
prefLabel
The GTPase Rem2 regulates synapse development and dendritic morphology
@en
P2860
P356
P1476
The GTPase Rem2 regulates synapse development and dendritic morphology
@en
P2093
Amy E Ghiretti
Suzanne Paradis
P2860
P304
P356
10.1002/DNEU.20868
P577
2011-05-01T00:00:00Z