The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation. - Wikidata - awgldk - TriplyDB

The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation.

The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation.

http://www.wikidata.org/entity/Q38407684

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Orm family proteins mediate sphingolipid homeostasis The eisosome core is composed of BAR domain proteins.A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy Sphingolipid signaling in metabolic disorders Phosphoinositides: tiny lipids with giant impact on cell regulation Phosphoinositide kinase signaling controls ER-PM cross-talk.Structural Insights into Assembly and Regulation of the Plasma Membrane Phosphatidylinositol 4-Kinase Complex A genome-wide screen for genes affecting eisosomes reveals Nce102 function in sphingolipid signaling.Iron, glucose and intrinsic factors alter sphingolipid composition as yeast cells enter stationary phase.Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast.Plasma membrane recruitment and activation of the AGC kinase Ypk1 is mediated by target of rapamycin complex 2 (TORC2) and its effector proteins Slm1 and Slm2.Regulation of Sphingolipid Biosynthesis by the Morphogenesis Checkpoint Kinase Swe1 The sphingolipid long-chain base-Pkh1/2-Ypk1/2 signaling pathway regulates eisosome assembly and turnover.Assembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3.A calcineurin-dependent switch controls the trafficking function of α-arrestin Aly1/Art6.TORC2 plasma membrane localization is essential for cell viability and restricted to a distinct domain.The yeast PH domain proteins Slm1 and Slm2 are targets of sphingolipid signaling during the response to heat stress.A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking TOR signaling is a determinant of cell survival in response to DNA damage.An assembly of proteins and lipid domains regulates transport of phosphatidylserine to phosphatidylserine decarboxylase 2 in Saccharomyces cerevisiae.Probing the membrane environment of the TOR kinases reveals functional interactions between TORC1, actin, and membrane trafficking in Saccharomyces cerevisiae Plasticity of PI4KIIIα interactions at the plasma membrane PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity Phosphatidylinositol 4-kinases: hostages harnessed to build panviral replication platforms Association of calcineurin with the COPI protein Sec28 and the COPII protein Sec13 revealed by quantitative proteomics A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast Cell growth control: little eukaryotes make big contributions.Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae.Keeping sphingolipid levels nORMal.Two phosphatidylinositol 4-kinases control lysosomal delivery of the Gaucher disease enzyme, β-glucocerebrosidase.Membranes in balance: mechanisms of sphingolipid homeostasis.The yeast sphingolipid signaling landscape.Interruption of inositol sphingolipid synthesis triggers Stt4p-dependent protein kinase C signaling.TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids.Genome-wide screen for inositol auxotrophy in Saccharomyces cerevisiae implicates lipid metabolism in stress response signaling Functional analysis of the Aspergillus nidulans kinome.Thematic review series: sphingolipids. New insights into sphingolipid metabolism and function in budding yeast.Modulation of sphingolipid metabolism by the phosphatidylinositol-4-phosphate phosphatase Sac1p through regulation of phosphatidylinositol in Saccharomyces cerevisiae.Cellular morphogenesis under stress is influenced by the sphingolipid pathway gene ISC1 and DNA integrity checkpoint genes in Saccharomyces cerevisiae.

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P2860

The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation.

http://www.wikidata.org/entity/Q38407684

description

2006 nî lūn-bûn

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The phosphatidylinositol 4,5-b ...... on in sphingolipid regulation.

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Molecular and Cellular Biology

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The phosphatidylinositol 4,5-b ...... on in sphingolipid regulation.

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Ainslie B Parsons

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Anjon Audhya

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Charles Boone

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Mitsuaki Tabuchi

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Scott D Emr

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P2860

Tsc13p is required for fatty acid elongation and localizes to a novel structure at the nuclear-vacuolar interface in Saccharomyces cerevisiae

Transformation of intact yeast cells treated with alkali cations

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

A comprehensive two-hybrid analysis to explore the yeast protein interactome

Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology.

Synthetic genetic array analysis of the PtdIns 4-kinase Pik1p identifies components in a Golgi-specific Ypt31/rab-GTPase signaling pathway.

Phospholipid metabolism regulated by a transcription factor sensing phosphatidic acid.

Calcineurin acts through the CRZ1/TCN1-encoded transcription factor to regulate gene expression in yeast

The yeast phosphatidylinositol-4-OH kinase pik1 regulates secretion at the Golgi.

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5861-5875

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10.1128/MCB.02403-05

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15

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26

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6939139

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16847337

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1592763

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