Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.
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Human Stem Cell-Derived Astrocytes: Specification and Relevance for Neurological DisordersFunctional Properties of Human Stem Cell-Derived Neurons in Health and DiseaseWhen stem cells grow old: phenotypes and mechanisms of stem cell agingModeling ALS with motor neurons derived from human induced pluripotent stem cellsTherapeutics from Adult Stem Cells and the Hype CurveAre aberrant phase transitions a driver of cellular aging?Small Molecules Modulate Chromatin Accessibility to Promote NEUROG2-Mediated Fibroblast-to-Neuron ReprogrammingMotor neuron vulnerability and resistance in amyotrophic lateral sclerosis.Stem cell models of Alzheimer's disease: progress and challenges.Comprehensive investigation of temporal and autism-associated cell type composition-dependent and independent gene expression changes in human brains.Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate.REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways.Concise Review: Progress and Challenges in Using Human Stem Cells for Biological and Therapeutics Discovery: Neuropsychiatric Disorders.The Aging EpigenomeStem cells for all ages, yet hostage to aging.Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells.FoxO3 regulates neuronal reprogramming of cells from postnatal and aging mice.Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts.Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding prioritiesInduced dopaminergic neurons: A new promise for Parkinson's disease.The translational potential of human induced pluripotent stem cells for clinical neurology : The translational potential of hiPSCs in neurology.Human induced pluripotent stem cells as a research tool in Alzheimer's disease.Altered neurite morphology and cholinergic function of induced pluripotent stem cell-derived neurons from a patient with Kleefstra syndrome and autismInduced Pluripotent Stem Cell Neuronal Models for the Study of Autophagy Pathways in Human Neurodegenerative Disease.New In Vitro Models to Study Amyotrophic Lateral Sclerosis.Human dermal fibroblasts in psychiatry research.An update on stem cell biology and engineering for brain development.Linking adult hippocampal neurogenesis with human physiology and disease.Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons.Insights into the pathogenic mechanisms of Chromosome 9 open reading frame 72 (C9orf72) repeat expansions.Nuclear transport dysfunction: a common theme in amyotrophic lateral sclerosis and frontotemporal dementia.DNA methylation in Parkinson's disease.Review: Induced pluripotent stem cell models of frontotemporal dementia.Multitasking Microglia and Alzheimer's Disease: Diversity, Tools and Therapeutic Targets.Rejuvenating Strategies for Stem Cell-Based Therapies in Aging.Neural Subtype Specification from Human Pluripotent Stem Cells.High content analysis in amyotrophic lateral sclerosis.Induced pluripotent stem cell technology: a decade of progress.Understanding Parkinson's Disease through the Use of Cell Reprogramming.Human induced pluripotent stem cells for modelling neurodevelopmental disorders.
P2860
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P2860
Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Directly Reprogrammed Human Ne ...... ted Nucleocytoplasmic Defects.
@en
type
label
Directly Reprogrammed Human Ne ...... ted Nucleocytoplasmic Defects.
@en
prefLabel
Directly Reprogrammed Human Ne ...... ted Nucleocytoplasmic Defects.
@en
P2093
P2860
P50
P1433
P1476
Directly Reprogrammed Human Ne ...... ated Nucleocytoplasmic Defects
@en
P2093
Apuã C M Paquola
Benjamin Campbell
Fred H Gage
Hyungjun Lee
Joseph R Herdy
Jürgen Winkler
Lena Böhnke
Manching Ku
Martin W Hetzer
Sean McGrath
P2860
P304
P356
10.1016/J.STEM.2015.09.001
P407
P577
2015-10-08T00:00:00Z