Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis.
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Molecular Genetic Markers in Acute Myeloid LeukemiaRecent advances and novel treatment paradigms in acute lymphocytic leukemiaIL-8 as mediator in the microenvironment-leukaemia network in acute myeloid leukaemia.Genomic dynamics associated with malignant transformation in IDH1 mutated gliomas.Oncogene- and drug resistance-associated alternative exon usage in acute myeloid leukemia (AML).Splicing factor mutations predict poor prognosis in patients with de novo acute myeloid leukemiaThe new provisional WHO entity 'RUNX1 mutated AML' shows specific genetics but no prognostic influence of dysplasia.Adult acute myeloid leukemia with trisomy 11 as the sole abnormality is characterized by the presence of five distinct gene mutations: MLL-PTD, DNMT3A, U2AF1, FLT3-ITD and IDH2.Isolated trisomy 13 in refractory anemia with excess blasts: report of two cases and a brief literature review of this possible association.Integrated Drug Expression Analysis for leukemia: an integrated in silico and in vivo approach to drug discovery.Clinical Relevance of RUNX1 and CBFB Alterations in Acute Myeloid Leukemia and Other Hematological Disorders.Close correlation of copy number aberrations detected by next-generation sequencing with results from routine cytogenetics in acute myeloid leukemia.A 4-gene expression score associated with high levels of Wilms Tumor-1 (WT1) expression is an adverse prognostic factor in acute myeloid leukaemia.Incidence and prognostic significance of isolated trisomies in adult acute myeloid leukemia: A population-based study from the Swedish AML registry.Acute myeloid leukemia with del(9q) is characterized by frequent mutations of NPM1, DNMT3A, WT1 and low expression of TLE4.Adults with Philadelphia chromosome-like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosisThe prognostic implication of SRSF2 mutations in Chinese patients with acute myeloid leukemia.Eradication of Acute Myeloid Leukemia with FLT3 Ligand-Targeted miR-150 Nanoparticles.ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.A 29-gene and cytogenetic score for the prediction of resistance to induction treatment in acute myeloid leukemia.A tumor profile in Patau syndrome (trisomy 13).Adenocarcinoma and polyposis of the colon in a 20-year-old patient with Trisomy 13: a case report.Screening for susceptibility genes in hereditary non-polyposis colorectal cancer.Priority-Lasso: a simple hierarchical approach to the prediction of clinical outcome using multi-omics dataN6-Methyladenosine Role in Acute Myeloid Leukaemia
P2860
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P2860
Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Isolated trisomy 13 defines a ...... some genes and poor prognosis.
@en
type
label
Isolated trisomy 13 defines a ...... some genes and poor prognosis.
@en
prefLabel
Isolated trisomy 13 defines a ...... some genes and poor prognosis.
@en
P2093
P50
P1433
P1476
Isolated trisomy 13 defines a ...... some genes and poor prognosis.
@en
P2093
Alexander Graf
Annika Dufour
Bernhard J Woermann
Bianka Ksienzyk
Christoph Röllig
Evelyn Zellmeier
Friedrich Stölzel
Helmut Blum
Karsten Spiekermann
Luise Hartmann
P304
P356
10.1182/BLOOD-2013-12-540716
P407
P577
2014-06-12T00:00:00Z