Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage. - Wikidata - awgldk - TriplyDB

Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage.

Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage.

http://www.wikidata.org/entity/Q38475385

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Functional genomics in osteoarthritis: Past, present, and future Genetic contribution to osteoarthritis development: current state of evidence Multiple levels of epigenetic control for bone biology and pathology Increased DNA Methylation and Reduced Expression of Transcription Factors in Human Osteoarthritis Cartilage.Genome-Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Subchondral Bone and Similarity to Overlying Cartilage.MicroRNAs and Autophagy: Fine Players in the Control of Chondrocyte Homeostatic Activities in Osteoarthritis.Epigenetic pathways regulating bone homeostasis: potential targeting for intervention of skeletal disorders.miR-105/Runx2 axis mediates FGF2-induced ADAMTS expression in osteoarthritis cartilage.Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils.Epigenetics and Osteoarthritis.Genome-wide DNA methylation study of hip and knee cartilage reveals embryonic organ and skeletal system morphogenesis as major pathways involved in osteoarthritis.DNA methylation regulates sclerostin (SOST) expression in osteoarthritic chondrocytes by bone morphogenetic protein 2 (BMP-2) induced changes in Smads binding affinity to the CpG region of SOST promoter.Renal involvement in lupus is characterized by unique DNA methylation changes in naïve CD4+ T cells.Differential DNA methylation and expression of inflammatory and zinc transporter genes defines subgroups of osteoarthritic hip patients Epigenetic mechanisms underlying the aberrant catabolic and anabolic activities of osteoarthritic chondrocytes.A Qualitative Model of the Differentiation Network in Chondrocyte Maturation: A Holistic View of Chondrocyte Hypertrophy.Autoimmune disease in the epigenetic era: how has epigenetics changed our understanding of disease and how can we expect the field to evolve?Methylation quantitative trait locus analysis of osteoarthritis links epigenetics with genetic risk Identification of differentially methylated regions in new genes associated with knee osteoarthritis.The Influence of DNA Methylation on Bone Cells.Associations between joint effusion in the knee and gene expression levels in the circulation: a meta-analysis.Phlpp1 facilitates post-traumatic osteoarthritis and is induced by inflammation and promoter demethylation in human osteoarthritis.Epigenetic and microRNA regulation during osteoarthritis development Osteoarthritis: toward a comprehensive understanding of pathological mechanism.Inflammation and epigenetic regulation in osteoarthritis.Emerging roles for long noncoding RNAs in skeletal biology and disease.miR128-1 inhibits the growth of glioblastoma multiforme and glioma stem-like cells via targeting BMI1 and E2F3.DNA Methylation Profiling in Chondrocyte Dedifferentiation In Vitro.DNA Methylation in Osteoarthritis.Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis.Epigenetics and Bone Remodeling.The Epigenomic Landscape in Osteoarthritis.Oxidative stress and chronic inflammation in osteoarthritis: can NRF2 counteract these partners in crime?ELF3 modulates type II collagen gene (COL2A1) transcription in chondrocytes by inhibiting SOX9-CBP/p300-driven histone acetyltransferase activity.The first international workshop on the epigenetics of osteoarthritis.Building and maintaining joints by exquisite local control of cell fate.The epigenetic landscape of age-related diseases: the geroscience perspective Genome-wide mapping of DNA hydroxymethylation in osteoarthritic chondrocytes.Transcriptional associations of osteoarthritis-mediated loss of epigenetic control in articular cartilage.DNA methylation of the RUNX2 P1 promoter mediates MMP13 transcription in chondrocytes.

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Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage.

http://www.wikidata.org/entity/Q38475385

description

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Genome-wide DNA methylation st ...... s in osteoarthritic cartilage.

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Genome-wide DNA methylation st ...... s in osteoarthritic cartilage.

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Genome-Wide DNA Methylation St ...... es in Osteoarthritic Cartilage

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Genome-wide DNA methylation st ...... es in osteoarthritic cartilage

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Genome-wide DNA methylation st ...... s in osteoarthritic cartilage.

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Genome-wide DNA methylation st ...... s in osteoarthritic cartilage.

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Amr H Sawalha

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Anand C Annan

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Lyle W Baker

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Madison Donica

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Mary Beth Humphrey

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Michael E Stevenson

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P2860

Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage

Autosomal dominant and recessive osteochondrodysplasias associated with the COL11A2 locus

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

The role of human HtrA1 in arthritic disease

A fibrillar collagen gene, Col11a1, is essential for skeletal morphogenesis

Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis

Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes.

Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates.

In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis.

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10

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66

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Matlock Jeffries

Judith A. James

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2014-10-01T00:00:00Z

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DNA methylation