Sporadic and Thorotrast-induced angiosarcomas of the liver manifest frequent and multiple point mutations in K-ras-2.

Sporadic and Thorotrast-induced angiosarcomas of the liver manifest frequent and multiple point mutations in K-ras-2.

Item
http://www.wikidata.org/entity/Q38476240
Plastics and carcinogenesis: the example of vinyl chlorideModeling human endothelial cell transformation in vascular neoplasiasFrequent k- ras -2 mutations and p16(INK4A)methylation in hepatocellular carcinomas in workers exposed to vinyl chlorideCase report: whole exome sequencing of primary cardiac angiosarcoma highlights potential for targeted therapiesAberrations in Angiogenic Signaling and MYC Amplifications are Distinguishing Features of Angiosarcoma.Epidemiology of primary and secondary liver cancers.Primary vascular tumors of bone: a spectrum of entities?Combined inhibition of MEK and mTOR has a synergic effect on angiosarcoma tumorgraftsOverexpression of VEGF 121 in immortalized endothelial cells causes conversion to slowly growing angiosarcoma and high level expression of the VEGF receptors VEGFR-1 and VEGFR-2 in vivo.Mutational status of K-ras and TP53 genes in primary sarcomas of the heartPharmacologic inhibition of MEK signaling prevents growth of canine hemangiosarcomaARF suppresses hepatic vascular neoplasia in a carcinogen-exposed murine model.Activation of endothelial ras signaling bypasses senescence and causes abnormal vascular morphogenesis.INK4a/ARF [corrected] inactivation with activation of the NF-κB/IL-6 pathway is sufficient to drive the development and growth of angiosarcoma.Combined mTOR and MEK inhibition is an effective therapy in a novel mouse model for angiosarcoma.
P2860

Sporadic and Thorotrast-induced angiosarcomas of the liver manifest frequent and multiple point mutations in K-ras-2.

Item
http://www.wikidata.org/entity/Q38476240
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Sporadic and Thorotrast-induce ...... le point mutations in K-ras-2.
@en
type
label
Sporadic and Thorotrast-induce ...... le point mutations in K-ras-2.
@en
prefLabel
Sporadic and Thorotrast-induce ...... le point mutations in K-ras-2.
@en
P1433
P1476
P2093
P304
P31
P433
P478
P577
P698
P1433
P1476
Sporadic and Thorotrast-induce ...... le point mutations in K-ras-2.
@en
P2093
P304
P31
P433
P478
P577
P698