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Myosins, Actin and AutophagyThe Roles of Microtubule-Based Transport at Presynaptic Nerve TerminalsExpanding the ubiquitin code through post-translational modificationTherapeutic targeting of autophagy in neurodegenerative and infectious diseasesStress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease.Ageing, neurodegeneration and brain rejuvenationTFEB at a glanceDNA Damage Response and Autophagy: A Meaningful PartnershipNuclear DNA damage signalling to mitochondria in ageingLoss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and NeurodegenerationAutophagy down regulates pro-inflammatory mediators in BV2 microglial cells and rescues both LPS and alpha-synuclein induced neuronal cell death.Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegenerationSGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production.Diversity-Oriented Stapling Yields Intrinsically Cell-Penetrant Inducers of Autophagy.Loss of spatacsin function alters lysosomal lipid clearance leading to upper and lower motor neuron degenerationSpecific phospholipid scramblases are involved in exposure of phosphatidylserine, an "eat-me" signal for phagocytes, on degenerating axonsCharacterization of Drosophila Saposin-related mutants as a model for lysosomal sphingolipid storage diseases.Granulostasis: Protein Quality Control of RNP Granules.Autophagy Is Involved in the Sevoflurane Anesthesia-Induced Cognitive Dysfunction of Aged Rats.The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms.mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy.Autophagy interaction with herpes simplex virus type-1 infectionPINK1 and Parkin cooperatively protect neurons against constitutively active TRP channel-induced retinal degeneration in Drosophila.TFEB Overexpression in the P301S Model of Tauopathy Mitigates Increased PHF1 Levels and Lipofuscin Puncta and Rescues Memory Deficits.Satellite Cells in Muscular Dystrophy - Lost in Polarity.The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB PerspectiveFunctional role of autophagy in gastric cancer.The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis.An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic miceSoluble adenylyl cyclase is essential for proper lysosomal acidificationMetformin Prevents Dopaminergic Neuron Death in MPTP/P-Induced Mouse Model of Parkinson's Disease via Autophagy and Mitochondrial ROS ClearanceRegulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy.Lessons from non-canonical splicingMisrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model.Traditional Chinese herbal extracts inducing autophagy as a novel approach in therapy of nonalcoholic fatty liver diseaseDecorin-inducible Peg3 Evokes Beclin 1-mediated Autophagy and Thrombospondin 1-mediated AngiostasisMahogunin Ring Finger-1 (MGRN1), a Multifaceted Ubiquitin Ligase: Recent Unraveling of Neurobiological Mechanisms.Cellular and molecular modifier pathways in tauopathies: the big picture from screening invertebrate models.Molecular definitions of autophagy and related processes.Formaldehyde Is a Potent Proteotoxic Stressor Causing Rapid Heat Shock Transcription Factor 1 Activation and Lys48-Linked Polyubiquitination of Proteins.
P2860
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P2860
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Compromised autophagy and neurodegenerative diseases.
@en
type
label
Compromised autophagy and neurodegenerative diseases.
@en
prefLabel
Compromised autophagy and neurodegenerative diseases.
@en
P356
P1476
Compromised autophagy and neurodegenerative diseases.
@en
P2093
David C Rubinsztein
Fiona M Menzies
P2888
P304
P356
10.1038/NRN3961
P407
P577
2015-06-01T00:00:00Z
P6179
1017581054