Sub-lytic C5b-9 induces functional changes in retinal pigment epithelial cells consistent with age-related macular degeneration.
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Mechanisms of age-related macular degenerationComplement factor H, vitronectin, and opticin are tyrosine-sulfated proteins of the retinal pigment epitheliumComplement modulation in the retinal pigment epithelium rescues photoreceptor degeneration in a mouse model of Stargardt disease.Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells.The membrane attack complex in aging human choriocapillaris: relationship to macular degeneration and choroidal thinning.Complement factors C1q, C3 and C5b-9 in the posterior sclera of guinea pigs with negative lens-defocused myopia.Retinal pigment epithelial cell death by the alternative complement cascade: role of membrane regulatory proteins, calcium, PKC, and oxidative stress.Retinal Pre-Conditioning by CD59a Knockout Protects against Light-Induced Photoreceptor Degeneration.Serum Th1 and Th17 related cytokines and autoantibodies in patients with Posner-Schlossman syndrome.Complement-mediated 'bystander' damage initiates host NLRP3 inflammasome activation.Target deletion of complement component 9 attenuates antibody-mediated hemolysis and lipopolysaccharide (LPS)-induced acute shock in mice.Targeting the complement system for the management of retinal inflammatory and degenerative diseases.Bisretinoid-mediated complement activation on retinal pigment epithelial cells is dependent on complement factor H haplotype.Role of tyrosine-sulfated proteins in retinal structure and functionComplement Membrane Attack and Tumorigenesis: A SYSTEMS BIOLOGY APPROACH.Exposure to the complement C5b-9 complex sensitizes 661W photoreceptor cells to both apoptosis and necroptosis.Fulminant Acute Ascending Hemorrhagic Myelitis Treated with Eculizumab.Age-related increases in amyloid beta and membrane attack complex: evidence of inflammasome activation in the rodent eye.Let's play a game of chutes and ladders: Lysosome fusion with the epithelial plasma membraneRetinal Pigment Epithelial Cells Mitigate the Effects of Complement Attack by Endocytosis of C5b-9.The role of complement activation in rhabdomyolysis-induced acute kidney injury.Modulation of three key innate immune pathways for the most common retinal degenerative diseases
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P2860
Sub-lytic C5b-9 induces functional changes in retinal pigment epithelial cells consistent with age-related macular degeneration.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Sub-lytic C5b-9 induces functi ...... -related macular degeneration.
@en
Sub-lytic C5b-9 induces functi ...... -related macular degeneration.
@en-gb
type
label
Sub-lytic C5b-9 induces functi ...... -related macular degeneration.
@en
Sub-lytic C5b-9 induces functi ...... -related macular degeneration.
@en-gb
prefLabel
Sub-lytic C5b-9 induces functi ...... -related macular degeneration.
@en
Sub-lytic C5b-9 induces functi ...... -related macular degeneration.
@en-gb
P2093
P2860
P356
P1433
P1476
Sub-lytic C5b-9 induces functi ...... e-related macular degeneration
@en
P2093
A Lommatzsch
D Pauleikhoff
J Williams
T R Hughes
P2860
P2888
P304
P356
10.1038/EYE.2011.109
P577
2011-05-20T00:00:00Z
P5875
P6179
1016221237