about
Mitochondria, cholesterol and cancer cell metabolismGlutathione and mitochondriaMitochondrial glutathione: features, regulation and role in diseaseCholesterol impairs the adenine nucleotide translocator-mediated mitochondrial permeability transition through altered membrane fluidityTrafficking of ganglioside GD3 to mitochondria by tumor necrosis factor-alphaDefective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice.Mitochondrial glutathione, a key survival antioxidant.Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol traffickingRedox control of liver function in health and diseaseProbiotic sonicates selectively induce mucosal immune cells apoptosis through ceramide generation via neutral sphingomyelinaseSpecific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione.Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell deathAcidic sphingomyelinase controls hepatic stellate cell activation and in vivo liver fibrogenesisIdentification and functional analysis of mutations in FAD-binding domain of mitochondrial glycerophosphate dehydrogenase in caucasian patients with type 2 diabetes mellitus.Growth arrest-specific protein 6 is hepatoprotective against murine ischemia/reperfusion injury.How is the liver primed or sensitized for alcoholic liver disease?Role of Mitochondria in Alcoholic Liver DiseaseInhibition of glutathione efflux in the perfused rat liver and isolated hepatocytes by organic anions and bilirubin. Kinetics, sidedness, and molecular formsExpression cloning of the cDNA for a polypeptide associated with rat hepatic sinusoidal reduced glutathione transport: characteristics and comparison with the canalicular transporter.Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma.S-Adenosyl-L-methionine and mitochondrial reduced glutathione depletion in alcoholic liver disease.Alcohol-induced liver disease: from molecular damage to treatment.Angiogenin secretion from hepatoma cells activates hepatic stellate cells to amplify a self-sustained cycle promoting liver cancer.Glutathione depletion impairs myogenic differentiation of murine skeletal muscle C2C12 cells through sustained NF-kappaB activationRedox regulation and signaling lipids in mitochondrial apoptosis.Cathepsin B overexpression due to acid sphingomyelinase ablation promotes liver fibrosis in Niemann-Pick disease.Alcohol-induced liver disease: when fat and oxidative stress meet.Glycosphingolipids and mitochondria: role in apoptosis and disease.Ceramide metabolism regulates autophagy and apoptotic cell death induced by melatonin in liver cancer cells.Gas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation.Oxidative stress and alcoholic liver disease.Hepatic mitochondrial glutathione: transport and role in disease and toxicity.Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis.Lysosomal Cholesterol Accumulation Sensitizes To Acetaminophen Hepatotoxicity by Impairing Mitophagy.Glycosphingolipids and cell death: one aim, many waysMyristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis.Sphingolipids and cell death.Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitisPharmacological modulation of sphingolipids and role in disease and cancer cell biology.Redox regulation of hepatocyte apoptosis.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
José C Fernández-Checa
@ast
José C Fernández-Checa
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José C Fernández-Checa
@es
José C Fernández-Checa
@nl
José C Fernández-Checa
@sl
type
label
José C Fernández-Checa
@ast
José C Fernández-Checa
@en
José C Fernández-Checa
@es
José C Fernández-Checa
@nl
José C Fernández-Checa
@sl
prefLabel
José C Fernández-Checa
@ast
José C Fernández-Checa
@en
José C Fernández-Checa
@es
José C Fernández-Checa
@nl
José C Fernández-Checa
@sl
P108
P1053
L-8342-2014
P106
P108
P21
P31
P3829
P496
0000-0003-3422-2990