about
A recurrent p.Arg92Trp variant in steroidogenic factor-1 (NR5A1) can act as a molecular switch in human sex developmentDesign, synthesis, binding and docking-based 3D-QSAR studies of 2-pyridylbenzimidazoles--a new family of high affinity CB1 cannabinoid ligands.Basolateral sorting of chloride channel 2 is mediated by interactions between a dileucine motif and the clathrin adaptor AP-1.Structural requirements of the human sodium-dependent bile acid transporter (hASBT): role of 3- and 7-OH moieties on binding and translocation of bile acids.APOA5 Q97X mutation identified through homozygosity mapping causes severe hypertriglyceridemia in a Chilean consanguineous family.An amphipathic alpha-helix in the prodomain of cocaine and amphetamine regulated transcript peptide precursor serves as its sorting signal to the regulated secretory pathway.Novel splice-affecting variants in CYP27A1 gene in two Chilean patients with Cerebrotendinous XanthomatosisCritical role of the first transmembrane domain of Cx26 in regulating oligomerization and functionDivergent metabolic phenotype between two sisters with congenital generalized lipodystrophy due to double AGPAT2 homozygous mutations. a clinical, genetic and in silico study.Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system.LC-MS/MS Method for the Simultaneous Determination of Free Urinary Steroids.Aldosterone Production and Signaling Dysregulation in Obesity.Usefulness and Pitfalls in Sodium Intake Estimation: Comparison of Dietary Assessment and Urinary Excretion in Chilean Children and Adults.Identification of novel 11β-HSD1 inhibitors by combined ligand- and structure-based virtual screening.Polymorphisms in the RAC1 gene are associated with hypertension risk factors in a Chilean pediatric population.11β-hydroxysteroid dehydrogenase type 2 polymorphisms and activity in a Chilean essential hypertensive and normotensive cohort.Docking and quantitative structure-activity relationship studies for the bisphenylbenzimidazole family of non-nucleoside inhibitors of HIV-1 reverse transcriptase.An eleven amino acid residue deletion expands the substrate specificity of acetyl xylan esterase II (AXE II) from Penicillium purpurogenum.Novel FXa Inhibitor Identification through Integration of Ligand- and Structure-Based Approaches.Computational modeling study of functional microdomains in cannabinoid receptor type 1.Dictyostelium discoideum as a surrogate host-microbe model for antivirulence screening in Pseudomonas aeruginosa PAO1.Cortisol/cortisone ratio and matrix metalloproteinase-9 activity are associated with pediatric primary hypertension.Citosine-Adenine-Repeat Microsatellite of 11β-hydroxysteroid dehydrogenase 2 Gene in Hypertensive Children.Molecular modeling of Trypanosoma cruzi glutamate cysteine ligase and investigation of its interactions with glutathioneCalpain inhibitors prevent p38 MAPK activation and germ cell apoptosis after heat stress in pubertal rat testesA new presentation of the chimeric CYP11B1/CYP11B2 gene with low prevalence of primary aldosteronism and atypical gene segregation patternThe Expression of RAC1 and Mineralocorticoid Pathway-Dependent Genes are Associated With Different Responses to Salt IntakeDesign, synthesis, biological evaluation and binding mode modeling of benzimidazole derivatives targeting the cannabinoid receptor type 1Pregnancy normalized familial hyperaldosteronism type I: a novel role for progesterone?Active acetylcholine receptors prevent the atrophy of skeletal muscles and favor reinnervationNext-Generation Sequencing Reveals Novel Genetic Variants (SRY, DMRT1, NR5A1, DHH, DHX37) in Adults With 46,XY DSD
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Carlos F. Lagos
@ast
Carlos F. Lagos
@en
Carlos F. Lagos
@es
Carlos F. Lagos
@nl
Carlos F. Lagos
@sl
type
label
Carlos F. Lagos
@ast
Carlos F. Lagos
@en
Carlos F. Lagos
@es
Carlos F. Lagos
@nl
Carlos F. Lagos
@sl
altLabel
CF Lagos
@en
Carlos Fernando Lagos
@en
Carlos Lagos
@en
prefLabel
Carlos F. Lagos
@ast
Carlos F. Lagos
@en
Carlos F. Lagos
@es
Carlos F. Lagos
@nl
Carlos F. Lagos
@sl
P1053
H-1860-2013
P106
P1153
23019461900
P21
P31
P3829
P496
0000-0002-5432-9747