about
Melanocortin-1 receptor signaling markedly induces the expression of the NR4A nuclear receptor subgroup in melanocytic cellsA single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye colorHuman pigmentation genes under environmental selectionMolecular genetics of human pigmentation diversityAnalysis of cultured human melanocytes based on polymorphisms within the SLC45A2/MATP, SLC24A5/NCKX5, and OCA2/P lociCharacterization of the Melanoma miRNAome by Deep SequencingThe recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome traffickingDerived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic EuropeanA non-synonymous mutation in the canine Pkd1 gene is associated with autosomal dominant polycystic kidney disease in Bull Terriers.NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF.IRF4 variants have age-specific effects on nevus count and predispose to melanoma.Eye colour: portals into pigmentation genes and ancestry.Molecular analysis of common polymorphisms within the human Tyrosinase locus and genetic association with pigmentation traitsProneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma.GWAS findings for human iris patterns: associations with variants in genes that influence normal neuronal pattern development.Interactive effects of MC1R and OCA2 on melanoma risk phenotypes.Melanocortin MC₁ receptor in human genetics and model systems.The NR4A2 nuclear receptor is recruited to novel nuclear foci in response to UV irradiation and participates in nucleotide excision repairMelanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation.Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up.A golden age of human pigmentation genetics.Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma.POU domain transcription factors: BRN2 as a regulator of melanocytic growth and tumourigenesis.Genetics of human iris colour and patterns.Sun-induced freckling: ephelides and solar lentigines.MC1R and NR4A receptors in cellular stress and DNA repair: implications for UVR protection.High incidence of primary melanomas in an MC1R RHC homozygote/CDKN2A mutant genotype patient.TLR3 drives IRF6-dependent IL-23p19 expression and p19/EBI3 heterodimer formation in keratinocytes.A UVR-induced G2-phase checkpoint response to ssDNA gaps produced by replication fork bypass of unrepaired lesions is defective in melanoma.Regulation of NR4A nuclear receptor expression by oncogenic BRAF in melanoma cells.SOX9 and SOX10 but not BRN2 are required for nestin expression in human melanoma cells.PPARgamma agonists attenuate proliferation and modulate Wnt/beta-catenin signalling in melanoma cells.Osteonectin downregulates E-cadherin, induces osteopontin and focal adhesion kinase activity stimulating an invasive melanoma phenotype.Receptor function, dominant negative activity and phenotype correlations for MC1R variant alleles.Genome-Wide Association Shows that Pigmentation Genes Play a Role in Skin Aging.Activation of the cAMP pathway by variant human MC1R alleles expressed in HEK and in melanoma cells.Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk.Co-expression of SOX9 and SOX10 during melanocytic differentiation in vitro.Heritability of naevus patterns in an adult twin cohort from the Brisbane Twin Registry: a cross-sectional study.Effect of MC1R variant allele status on MSH-ligand induction of dopachrome tautomerase in melanocytes co-cultured with keratinocytes.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Richard A Sturm
@ast
Richard A Sturm
@en
Richard A Sturm
@es
Richard A Sturm
@sl
type
label
Richard A Sturm
@ast
Richard A Sturm
@en
Richard A Sturm
@es
Richard A Sturm
@sl
altLabel
Richard Sturm
@en
prefLabel
Richard A Sturm
@ast
Richard A Sturm
@en
Richard A Sturm
@es
Richard A Sturm
@sl
P1053
C-9943-2009
P106
P21
P31
P3829
P496
0000-0003-1301-0294