An efficient Fmoc-SPPS approach for the generation of thioester peptide precursors for use in native chemical ligation.
about
Advances in Fmoc solid-phase peptide synthesisProtease-resistant peptide design-empowering nature's fragile warriors against HIVA highly scalable peptide-based assay system for proteomicsDelivery and tracking of quantum dot peptide bioconjugates in an intact developing avian brainSemisynthetic Nanoreactor for Reversible Single-Molecule Covalent ChemistryApplication of the protein semisynthesis strategy to the generation of modified chromatinFmoc-based peptide thioester synthesis with self-purifying effect: heading to native chemical ligation in parallel formats.Tidbits for the synthesis of bis(2-sulfanylethyl)amido (SEA) polystyrene resin, SEA peptides and peptide thioesters.Development and application of serine/threonine ligation for synthetic protein chemistry.Expressed protein ligation: a resourceful tool to study protein structure and function.Expanding the chemical toolbox for the synthesis of large and uniquely modified proteins.Chemical and semisynthesis of posttranslationally modified proteins.Realizing serine/threonine ligation: scope and limitations and mechanistic implication thereofPeptide and glycopeptide dendrimers and analogous dendrimeric structures and their biomedical applications.Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries.Synthesis of thioester peptides for the incorporation of thioamides into proteins by native chemical ligation.A semisynthetic strategy to generate phosphorylated and acetylated histone H2B.Histones: at the crossroads of peptide and protein chemistry.Rapid optimization of labeled ubiquitinated peptides for monitoring deubiquitinases activities.Shifting Native Chemical Ligation into Reverse through N→S Acyl Transfer.Biological activities of natural and engineered cyclotides, a novel molecular scaffold for peptide-based therapeutics.Cyclotides, a novel ultrastable polypeptide scaffold for drug discoveryInterrogation of MDM2 phosphorylation in p53 activation using native chemical ligation: the functional role of Ser17 phosphorylation in MDM2 reexamined.Native chemical ligation of thioamide-containing peptides: development and application to the synthesis of labeled α-synuclein for misfolding studiesNanoporous Superhydrophobic Coatings that Promote the Extended Release of Water-Labile Quorum Sensing Inhibitors and Enable Long-Term Modulation of Quorum Sensing in Staphylococcus aureus.O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's diseaseCharacterization of semisynthetic and naturally Nα-acetylated α-synuclein in vitro and in intact cells: implications for aggregation and cellular properties of α-synuclein.Semisynthetic protein nanoreactor for single-molecule chemistryCharacterization of structural elements in native autoinducing peptides and non-native analogues that permit the differential modulation of AgrC-type quorum sensing receptors in Staphylococcus aureus.A reversible protection strategy to improve Fmoc-SPPS of peptide thioesters by the N-Acylurea approach.Hybrid phase ligation for efficient synthesis of histone proteins.Chemical and biological production of cyclotides.Protein chemical synthesis by serine and threonine ligationOral activity of a nature-derived cyclic peptide for the treatment of multiple sclerosis.A two-state activation mechanism controls the histone methyltransferase Suv39h1.Chemical Synthesis of Phosphorylated Histone H2A at Tyr57 Reveals Insight into the Inhibition Mode of the SAGA Deubiquitinating Module.Chemical approaches for studying histone modifications.Post-assembly functionalization of supramolecular nanostructures with bioactive peptides and fluorescent proteins by native chemical ligation.Nonenzymatic ubiquitylation.9-Fluorenylmethoxycarbonyl-based solid-phase synthesis of peptide α-thioesters.
P2860
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P2860
An efficient Fmoc-SPPS approach for the generation of thioester peptide precursors for use in native chemical ligation.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
An efficient Fmoc-SPPS approac ...... e in native chemical ligation.
@en
type
label
An efficient Fmoc-SPPS approac ...... e in native chemical ligation.
@en
prefLabel
An efficient Fmoc-SPPS approac ...... e in native chemical ligation.
@en
P2860
P356
P1476
An efficient Fmoc-SPPS approac ...... e in native chemical ligation.
@en
P2093
Juan B Blanco-Canosa
Philip E Dawson
P2860
P304
P356
10.1002/ANIE.200705471
P407
P577
2008-01-01T00:00:00Z