Eps15 is recruited to the plasma membrane upon epidermal growth factor receptor activation and localizes to components of the endocytic pathway during receptor internalization.
about
Numb is an endocytic proteinTroyer syndrome protein spartin is mono-ubiquitinated and functions in EGF receptor traffickingHrs-2 regulates receptor-mediated endocytosis via interactions with Eps15Association of insulin-like growth factor 1 receptor with EHD1 and SNAP29A role for epsin N-terminal homology/AP180 N-terminal homology (ENTH/ANTH) domains in tubulin bindingInteractions of phocein with nucleoside-diphosphate kinase, Eps15, and Dynamin ISTAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomesRecycling of the epidermal growth factor receptor is mediated by a novel form of the clathrin adaptor protein Eps15The ErbB signaling network: receptor heterodimerization in development and cancerCbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pitsRegulation of ubiquitin-dependent cargo sorting by multiple endocytic adaptors at the plasma membraneCharacterization of EHD4, an EH domain-containing protein expressed in the extracellular matrix.The Eps15 homology (EH) domain.Regulation of receptor tyrosine kinase signaling by endocytic trafficking.Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinases.Localization of the Rsp5p ubiquitin-protein ligase at multiple sites within the endocytic pathway.Relationships between EGFR signaling-competent and endocytosis-competent membrane microdomainsThe function of yeast epsin and Ede1 ubiquitin-binding domains during receptor internalization.Multiple signals regulate trafficking of the mannose 6-phosphate-uncovering enzyme.Bioengineering strategies for designing targeted cancer therapiesUIM domain-dependent recruitment of the endocytic adaptor protein Eps15 to ubiquitin-enriched endosomes.The endocytic adaptor Eps15 controls marginal zone B cell numbersThe hereditary spastic paraplegia protein spartin localises to mitochondria.Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling.Molecular imaging of epidermal growth factor receptor kinase activity.Exploring kinase inhibitors as therapies for human arenavirus infections.Eps15R is required for bone morphogenetic protein signalling and differentially compartmentalizes with Smad proteins.Regulation of endocytic clathrin dynamics by cargo ubiquitinationTyrosine phosphorylation of Eps15 is required for ligand-regulated, but not constitutive, endocytosis.Epidermal growth factor and membrane trafficking. EGF receptor activation of endocytosis requires Rab5aEps15 mediates vesicle trafficking from the trans-Golgi network via an interaction with the clathrin adaptor AP-1.Endocytic downregulation of ErbB receptors: mechanisms and relevance in cancerRole of HRB in clathrin-dependent endocytosis.Ligand-based targeted therapy for cancer tissue.An endosomally localized isoform of Eps15 interacts with Hrs to mediate degradation of epidermal growth factor receptor.PHD3 regulates EGFR internalization and signalling in tumours.Eps15 and Dap160 control synaptic vesicle membrane retrieval and synapse development.Large-scale proteomic analysis of tyrosine-phosphorylation induced by T-cell receptor or B-cell receptor activation reveals new signaling pathways.Genistein treatment of cells inhibits arenavirus infection.A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling.
P2860
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P2860
Eps15 is recruited to the plasma membrane upon epidermal growth factor receptor activation and localizes to components of the endocytic pathway during receptor internalization.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Eps15 is recruited to the plas ...... ring receptor internalization.
@en
type
label
Eps15 is recruited to the plas ...... ring receptor internalization.
@en
prefLabel
Eps15 is recruited to the plas ...... ring receptor internalization.
@en
P2093
P2860
P356
P1476
Eps15 is recruited to the plas ...... uring receptor internalization
@en
P2093
F Belleudi
M R Torrisi
P G Pelicci
P P Di Fiore
P2860
P304
P356
10.1091/MBC.10.2.417
P577
1999-02-01T00:00:00Z