Mutagenesis of the active-site cysteine in the ubiquitin-specific protease contained in large tegument protein pUL36 of pseudorabies virus impairs viral replication in vitro and neuroinvasion in vivo.
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Viral Mimicry to Usurp Ubiquitin and SUMO Host PathwaysViral and host control of cytomegalovirus maturationViral OTU deubiquitinases: a structural and functional comparisonDynamic ubiquitination drives herpesvirus neuroinvasionMurine Cytomegalovirus Deubiquitinase Regulates Viral Chemokine Levels To Control Inflammation and PathogenesisA herpesvirus encoded deubiquitinase is a novel neuroinvasive determinantA wide extent of inter-strain diversity in virulent and vaccine strains of alphaherpesviruses.Update on herpes virus infections of the nervous system.Blocking ESCRT-mediated envelopment inhibits microtubule-dependent trafficking of alphaherpesviruses in vitro.Caspase-1 promotes Epstein-Barr virus replication by targeting the large tegument protein deneddylase to the nucleus of productively infected cells.Autocatalytic activity of the ubiquitin-specific protease domain of herpes simplex virus 1 VP1-2.Knockout of Epstein-Barr virus BPLF1 retards B-cell transformation and lymphoma formation in humanized mice.The Epstein-Barr virus (EBV) deubiquitinating enzyme BPLF1 reduces EBV ribonucleotide reductase activity.Herpes simplex virus 1 ubiquitin-specific protease UL36 inhibits beta interferon production by deubiquitinating TRAF3.Herpesvirus transport to the nervous system and back again.Cleavage specificity of the UL48 deubiquitinating protease activity of human cytomegalovirus and the growth of an active-site mutant virus in cultured cells.Viral avoidance and exploitation of the ubiquitin system.Viral takeover of the host ubiquitin system.The ubiquitin-conjugating system: multiple roles in viral replication and infection.Nuclear targeting of human cytomegalovirus large tegument protein pUL48 is essential for viral growth.Tsg101 interacts with herpes simplex virus 1 VP1/2 and is a substrate of VP1/2 ubiquitin-specific protease domain activity.Assembly and Egress of an Alphaherpesvirus Clockwork.Random transposon-mediated mutagenesis of the essential large tegument protein pUL36 of pseudorabies virus.A gammaherpesvirus ubiquitin-specific protease is involved in the establishment of murine gammaherpesvirus 68 infection.The Translesion Polymerase Pol η Is Required for Efficient Epstein-Barr Virus Infectivity and Is Regulated by the Viral Deubiquitinating Enzyme BPLF1.Epstein-Barr virus BPLF1 deubiquitinates PCNA and attenuates polymerase η recruitment to DNA damage sitesKaposi's sarcoma-associated herpesvirus encodes a viral deubiquitinase.Functional Interaction Between the ESCRT-I Component TSG101 and the HSV-1 Tegument Ubiquitin Specific Protease.The Rad6/18 ubiquitin complex interacts with the Epstein-Barr virus deubiquitinating enzyme, BPLF1, and contributes to virus infectivity.The pUL37 tegument protein guides alpha-herpesvirus retrograde axonal transport to promote neuroinvasion.
P2860
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P2860
Mutagenesis of the active-site cysteine in the ubiquitin-specific protease contained in large tegument protein pUL36 of pseudorabies virus impairs viral replication in vitro and neuroinvasion in vivo.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Mutagenesis of the active-site ...... tro and neuroinvasion in vivo.
@en
type
label
Mutagenesis of the active-site ...... tro and neuroinvasion in vivo.
@en
prefLabel
Mutagenesis of the active-site ...... tro and neuroinvasion in vivo.
@en
P2093
P2860
P356
P1433
P1476
Mutagenesis of the active-site ...... tro and neuroinvasion in vivo.
@en
P2093
Barbara G Klupp
Christina Maresch
Harald Granzow
Jens P Teifke
Sindy Böttcher
P2860
P304
P356
10.1128/JVI.00280-08
P407
P577
2008-04-09T00:00:00Z