Osteoblastic niche supports the growth of quiescent multiple myeloma cells.
about
Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction?Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche.Dynamic interplay between bone and multiple myeloma: emerging roles of the osteoblastIbrutinib inhibits BTK-driven NF-κB p65 activity to overcome bortezomib-resistance in multiple myeloma.Dissecting the multiple myeloma-bone microenvironment reveals new therapeutic opportunitiesMultiple myeloma in the marrow: pathogenesis and treatments.Hedgehog and retinoid signaling alters multiple myeloma microenvironment and generates bortezomib resistance.Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins.A novel 3D mesenchymal stem cell model of the multiple myeloma bone marrow niche: biologic and clinical applications.The osteoblastic niche in the context of multiple myeloma.Downregulation of estrogen receptor and modulation of growth of breast cancer cell lines mediated by paracrine stromal cell signals.Tumor-Initiating Cells: Emerging Biophysical Methods of Isolation.ROS-Induced CXCR4 Signaling Regulates Mantle Cell Lymphoma (MCL) Cell Survival and Drug Resistance in the Bone Marrow Microenvironment via Autophagy.Differential PAX5 levels promote malignant B-cell infiltration, progression and drug resistance, and predict a poor prognosis in MCL patients independent of CCND1.Adipose, Bone, and Myeloma: Contributions from the Microenvironment.Myeloma impairs mature osteoblast function but causes early expansion of osteo-progenitors: temporal changes in bone physiology and gene expression in the KMS12BM model.Emerging Roles of Osteoclasts in the Modulation of Bone Microenvironment and Immune Suppression in Multiple MyelomaHIF-1α and rapamycin act as gerosuppressant in multiple myeloma cells upon genotoxic stress.Melphalan modifies the bone microenvironment by enhancing osteoclast formation.Retinoic acid, CYP26, and drug resistance in the stem cell niche.Multiple Myeloma Exemplifies a Model of Cancer Based on Tissue Disruption as the Initiator Event
P2860
Q26785497-7FEEDE43-04F8-463F-8160-89BB7F9277CDQ27316833-019FF34A-C9DA-46AB-95C1-5B10C69C7219Q36086488-84E33D2F-E61C-433B-A38A-C2F880A205E8Q36183770-45B23984-D58C-4DF0-B71D-F4F78789999DQ36447553-B4736179-BD96-4819-AFDD-168B79EA9AF4Q36725401-7B690E1E-AE36-4366-A6FA-A3E9FE75F3BAQ37452148-FBEC7E26-CC59-48E5-9CD6-046A17B62365Q37589988-27DC79DA-8F50-45D2-A956-71E32B337140Q37709866-DE9BE443-398A-498F-8E6C-225A24A19DE9Q38271428-80A20DBE-F8E3-46F1-842A-946F6A9523E1Q38730755-64CBF818-2A13-44F9-8F57-49FF3A856D9BQ38824383-4C58F8DC-4123-4B50-902F-B4CF09E15E6CQ38836849-C1829E42-42B5-4EA5-924B-7E3F1CD673BBQ38864150-4D69447D-C57B-46CA-9373-B545393F85CFQ38876521-DED0A572-29E0-400B-829E-B33EE85672F2Q40108030-B67ADC0C-8331-476C-ABAA-4CA63EF3B0C7Q41370609-5386BBC7-EC36-4AFC-9C82-6556D9370DE8Q41449149-B7B739AB-F5D6-4F53-AA39-358C540247CAQ42366597-3A73C8D9-DF50-45C0-B1A0-BE3A2AA80AF8Q48015915-563D059D-49A5-474F-BE2A-9F9748ACC584Q58754109-24332849-2A04-4618-A8C8-D43403F9FA38
P2860
Osteoblastic niche supports the growth of quiescent multiple myeloma cells.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Osteoblastic niche supports the growth of quiescent multiple myeloma cells.
@en
type
label
Osteoblastic niche supports the growth of quiescent multiple myeloma cells.
@en
prefLabel
Osteoblastic niche supports the growth of quiescent multiple myeloma cells.
@en
P2093
P2860
P1433
P1476
Osteoblastic niche supports the growth of quiescent multiple myeloma cells.
@en
P2093
Larry Kwak
Michael Wang
Nami McCarty
Zheng Chen
P2860
P304
P356
10.1182/BLOOD-2013-07-517136
P407
P577
2014-01-14T00:00:00Z