Echo-planar spectroscopic imaging with dual-readout alternated gradients (DRAG-EPSI) at 7 T: Application for 2-hydroxyglutarate imaging in glioma patients.

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Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner.

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Echo-planar spectroscopic imaging with dual-readout alternated gradients (DRAG-EPSI) at 7 T: Application for 2-hydroxyglutarate imaging in glioma patients.

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Echo-planar spectroscopic imag ...... te imaging in glioma patients.

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Echo-planar spectroscopic imag ...... te imaging in glioma patients.

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Echo-planar spectroscopic imag ...... te imaging in glioma patients.

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P1476

Echo-planar spectroscopic imag ...... ate imaging in glioma patients

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Bruce E Mickey

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Changho Choi

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Edward Pan

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Elizabeth A Maher

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Jeannie Baxter

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Marco C Pinho

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Michael Levy

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Sandeep K Ganji

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Toral R Patel

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Vivek Tiwari

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P2860

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

An integrated genomic analysis of human glioblastoma multiforme

IDH1 and IDH2 mutations in gliomas

An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

Achieving sufficient spectral bandwidth for volumetric 1H echo-planar spectroscopic imaging at 4 Tesla.

MR spectroscopic imaging: principles and recent advances.

1H MR spectroscopy of brain tumours and masses.

Short-echo three-dimensional H-1 MR spectroscopic imaging of patients with glioma at 7 Tesla for characterization of differences in metabolite levels

P304

1851-1861

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scholarly article

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10.1002/MRM.26884

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Zhongxu An

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2017-08-22T00:00:00Z

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28833542

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Echo-planar spectroscopic imaging with dual-readout alternated gradients (DRAG-EPSI) at 7 T: Application for 2-hydroxyglutarate imaging in glioma patients.

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P2860

P2860

Echo-planar spectroscopic imaging with dual-readout alternated gradients (DRAG-EPSI) at 7 T: Application for 2-hydroxyglutarate imaging in glioma patients.

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