Cooperation between both Wnt/{beta}-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion. - Wikidata - awgldk - TriplyDB

Cooperation between both Wnt/{beta}-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion.

Cooperation between both Wnt/{beta}-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion.

http://www.wikidata.org/entity/Q38617784

about

Challenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?Aryl hydrocarbon receptor/cytochrome P450 1A1 pathway mediates breast cancer stem cells expansion through PTEN inhibition and β-Catenin and Akt activation Activation of Wnt/β-catenin protein signaling induces mitochondria-mediated apoptosis in hematopoietic progenitor cells β-catenin and PI3Kδ inhibition expands precursor Th17 cells with heightened stemness and antitumor activity.C1QBP suppresses cell adhesion and metastasis of renal carcinoma cells Thermodynamics in Gliomas: Interactions between the Canonical WNT/Beta-Catenin Pathway and PPAR Gamma Ribosomal DNA copy number loss and sequence variation in cancer Inhibiting glycogen synthase kinase-3 mitigates the hematopoietic acute radiation syndrome in mice WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear β-Catenin depend on active PI3K signaling.SHIP1 regulates MSC numbers and their osteolineage commitment by limiting induction of the PI3K/Akt/β-catenin/Id2 axis.A novel human glycoprotein ACA is an upstream regulator of human hematopoiesis.Oncostatin M maintains the hematopoietic microenvironment in the bone marrow by modulating adipogenesis and osteogenesis.BCR-ABL1-associated reduction of beta catenin antagonist Chibby1 in chronic myeloid leukemia Cytokine expression patterns and mesenchymal stem cell karyotypes from the bone marrow microenvironment of patients with myelodysplastic syndromes.The PI3K pathway balances self-renewal and differentiation of nephron progenitor cells through β-catenin signaling.IP3 3-kinase B controls hematopoietic stem cell homeostasis and prevents lethal hematopoietic failure in mice Wnt3a protein reduces growth factor-driven expansion of human hematopoietic stem and progenitor cells in serum-free cultures.Function of cancer associated genes revealed by modern univariate and multivariate association tests.Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells Small-molecule inhibitors targeting INK4 protein p18(INK4C) enhance ex vivo expansion of haematopoietic stem cells.Influence maximization in time bounded network identifies transcription factors regulating perturbed pathways Overshoot during phenotypic switching of cancer cell populations FGF signaling facilitates postinjury recovery of mouse hematopoietic system.Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways.The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML.MicroRNA-374a activates Wnt/β-catenin signaling to promote breast cancer metastasis Apc regulates the function of hematopoietic stem cells largely through β-catenin-dependent mechanisms.Hematopoietic and Leukemic Stem Cells Have Distinct Dependence on Tcf1 and Lef1 Transcription Factors.Control of adult stem cells in vivo by a dynamic physiological environment: diet-dependent systemic factors in Drosophila and beyond.Modeling the Pro-inflammatory Tumor Microenvironment in Acute Lymphoblastic Leukemia Predicts a Breakdown of Hematopoietic-Mesenchymal Communication Networks Isolation and characterization of intestinal stem cells based on surface marker combinations and colony-formation assay.Regulation of human hematopoietic stem cell self-renewal by the microenvironment's control of retinoic acid signaling Maternal imprinting at the H19-Igf2 locus maintains adult haematopoietic stem cell quiescence.Distinct signaling programs control human hematopoietic stem cell survival and proliferation.A caspase-dependent pathway is involved in Wnt/β-catenin signaling promoted apoptosis in Bacillus Calmette-Guerin infected RAW264.7 macrophages.Gankyrin sustains PI3K/GSK-3β/β-catenin signal activation and promotes colorectal cancer aggressiveness and progression.Regulation of epithelial proliferation by tight junction proteins.Insights into cancer metastasis from a clinicopathologic perspective: Epithelial-Mesenchymal Transition is not a necessary step.Hematopoietic stem cell expansion: challenges and opportunities.Wnt signaling in normal and malignant hematopoiesis.

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P2860

Cooperation between both Wnt/{beta}-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion.

http://www.wikidata.org/entity/Q38617784

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2011 nî lūn-bûn

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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2011年學術文章

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2011年學術文章

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name

Cooperation between both Wnt/{ ...... ll self-renewal and expansion.

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Cooperation between both Wnt/{ ...... ll self-renewal and expansion.

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Cooperation between both Wnt/{ ...... ll self-renewal and expansion.

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Genes & Development

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Cooperation between both Wnt/{ ...... ll self-renewal and expansion.

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Jeffrey S Haug

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John M Perry

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Justin C Grindley

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Linheng Li

http://www.w3.org/2001/XMLSchema#string

Ryohichi Sugimura

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Sheng Ding

http://www.w3.org/2001/XMLSchema#string

Xi C He

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P2860

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells

Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells

Epidermal homeostasis: a balancing act of stem cells in the skin

PTEN-deficient intestinal stem cells initiate intestinal polyposis.

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

Stem cells, cancer, and cancer stem cells

Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration

Asymmetric and symmetric stem-cell divisions in development and cancer

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1928-1942

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10.1101/GAD.17421911

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18

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25

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51617906

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21890648

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3185965

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