The art of CHO cell engineering: A comprehensive retrospect and future perspectives.
about
Protein stability: a crystallographer's perspectiveA short synthetic chimeric sequence harboring matrix attachment region/PSAR2 increases transgene expression in Chinese hamster ovary cells.Comparative study of therapeutic antibody candidates derived from mini-pool and clonal cell lines.New Mammalian Expression Systems.Application of CRISPR/Cas9 Genome Editing to Improve Recombinant Protein Production in CHO Cells.miRNA engineering of CHO cells facilitates production of difficult-to-express proteins and increases success in cell line development.Engineering CHO cells with an oncogenic KIT improves cells growth, resilience to stress and productivity.Cellular engineering for therapeutic protein production: product quality, host modification, and process improvement.Reduction of ammonia and lactate through the coupling of glutamine synthetase selection and downregulation of lactate dehydrogenase-A in CHO cells.Fam60A plays a role for production stabilities of recombinant CHO cell lines.Disruption of the gene C12orf35 leads to increased productivities in recombinant CHO cell lines.miR-143 targets MAPK7 in CHO cells and induces a hyperproductive phenotype to enhance production of difficult-to-express proteins.Production of recombinant coagulation factors: Are humans the best host cells?Production of a Chikungunya Vaccine Using a CHO Cell and Attenuated Viral-Based Platform Technology.Regulation of miR-29b-1/a transcription and identification of target mRNAs in CHO-K1 cells.The emerging role of systems biology for engineering protein production in CHO cells.Site-specific chromosomal gene insertion: Flp recombinase versus Cas9 nuclease.Methods for Using Small Non-Coding RNAs to Improve Recombinant Protein Expression in Mammalian Cells.Enhanced IgG1 production by overexpression of nuclear factor kappa B inhibitor zeta (NFKBIZ) in Chinese hamster ovary cells.CHO-Omics Review: The Impact of Current and Emerging Technologies on Chinese Hamster Ovary Based Bioproduction.Identifying HIPK1 as Target of miR-22-3p Enhancing Recombinant Protein Production From HEK 293 Cell by Using Microarray and HTP siRNA Screen.Transient and stable CHO expression, purification and characterization of novel hetero-dimeric bispecific IgG antibodies.Identification of a potent MAR element from the human genome and assessment of its activity in stably transfected CHO cells.CD147 overexpression promotes tumorigenicity in Chinese hamster ovary cells.Cell Line Techniques and Gene Editing Tools for Antibody Production: A Review.
P2860
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P2860
The art of CHO cell engineering: A comprehensive retrospect and future perspectives.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
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2015年學術文章
@zh-hant
name
The art of CHO cell engineering: A comprehensive retrospect and future perspectives.
@en
type
label
The art of CHO cell engineering: A comprehensive retrospect and future perspectives.
@en
prefLabel
The art of CHO cell engineering: A comprehensive retrospect and future perspectives.
@en
P1476
The art of CHO cell engineering: A comprehensive retrospect and future perspectives.
@en
P2093
Kerstin Otte
René Handrick
P304
P356
10.1016/J.BIOTECHADV.2015.10.015
P577
2015-10-30T00:00:00Z