Increased expression of integrin alphavbeta5 induces the myofibroblastic differentiation of dermal fibroblasts.
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Integrin-β5 and zyxin mediate formation of ventral stress fibers in response to transforming growth factor βMyofibroblast contraction activates latent TGF-beta1 from the extracellular matrixMicroRNAs Regulating Signaling Pathways: Potential Biomarkers in Systemic SclerosisFibroblasts and myofibroblasts in wound healingExtracellular matrix as a contextual determinant of transforming growth factor-β signaling in epithelial-mesenchymal transition and in cancerαv integrins: key regulators of tissue fibrosisTGF-β activation and function in immunity.Tenascin-X promotes epithelial-to-mesenchymal transition by activating latent TGF-βIntegrins αvβ5 and αvβ3 promote latent TGF-β1 activation by human cardiac fibroblast contractionPeriostin in Mature Stage Localized Scleroderma.Transcriptional changes in bone marrow stromal cells of patients with heart failure.The role of integrin alpha(v)beta (8) in neonatal hypoxic-ischemic brain injuryThe fibroblast integrin alpha11beta1 is induced in a mechanosensitive manner involving activin A and regulates myofibroblast differentiation.Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription.A possible contribution of altered cathepsin B expression to the development of skin sclerosis and vasculopathy in systemic sclerosisDegradation of internalized αvβ5 integrin is controlled by uPAR bound uPA: effect on β1 integrin activity and α-SMA stress fiber assembly.Fibrosis: recent advances in myofibroblast biology and new therapeutic perspectives.Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies.Fibrosis, vascular activation, and immune abnormalities resembling systemic sclerosis in bleomycin-treated Fli-1-haploinsufficient miceGenetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models.SPARC promotes pericyte recruitment via inhibition of endoglin-dependent TGF-β1 activity.Expansion on extracellular matrix deposited by human bone marrow stromal cells facilitates stem cell proliferation and tissue-specific lineage potential.Reducing affinity of αvβ8 interactions with latent TGFβ: dialling down fibrosis.Molecular and cellular mechanisms of pulmonary fibrosis.Canstatin inhibits hypoxia-induced apoptosis through activation of integrin/focal adhesion kinase/Akt signaling pathway in H9c2 cardiomyoblasts.Tissue level, activation and cellular localisation of TGF-beta1 and association with survival in gastric cancer patientsα-Smooth muscle actin is an inconsistent marker of fibroblasts responsible for force-dependent TGFβ activation or collagen production across multiple models of organ fibrosis.The matricellular protein CCN1 enhances TGF-β1/SMAD3-dependent profibrotic signaling in fibroblasts and contributes to fibrogenic responses to lung injury.Ovarian normal and tumor-associated fibroblasts retain in vivo stromal characteristics in a 3-D matrix-dependent mannerThe impact of Fli1 deficiency on the pathogenesis of systemic sclerosisTargeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs.A novel cell adhesion region in tropoelastin mediates attachment to integrin αVβ5.Matrix-regulated integrin αvβ5 maintains α5β1-dependent desmoplastic traits prognostic of neoplastic recurrence.Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities.Integrin-TGF-beta crosstalk in fibrosis, cancer and wound healing.Systemic sclerosis sera affect fibrillin-1 deposition by dermal blood microvascular endothelial cells: therapeutic implications of cyclophosphamide.The pathogenesis of idiopathic pulmonary fibrosis.Cell-extracellular matrix interactions in normal and diseased skin.Integrin-mediated regulation of TGFβ in fibrosisTargeted therapies for systemic sclerosis.
P2860
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P2860
Increased expression of integrin alphavbeta5 induces the myofibroblastic differentiation of dermal fibroblasts.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Increased expression of integr ...... tiation of dermal fibroblasts.
@en
type
label
Increased expression of integr ...... tiation of dermal fibroblasts.
@en
prefLabel
Increased expression of integr ...... tiation of dermal fibroblasts.
@en
P2093
P2860
P1476
Increased expression of integr ...... tiation of dermal fibroblasts.
@en
P2093
Hironobu Ihn
Kenichi Yamane
Kunihiko Tamaki
Masatoshi Jinnin
Yoshihide Asano
P2860
P304
P356
10.2353/AJPATH.2006.041306
P407
P577
2006-02-01T00:00:00Z