Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania.
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Drug resistance analysis by next generation sequencing in LeishmaniaAntimicrobial-induced DNA damage and genomic instability in microbial pathogensPlasticity of the Leishmania genome leading to gene copy number variations and drug resistanceMiltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasisMultiple mutations in heterogeneous miltefosine-resistant Leishmania major population as determined by whole genome sequencingLeishmania donovani develops resistance to drug combinationsProteomic and genomic analyses of antimony resistant Leishmania infantum mutantAntileishmanial activity of semisynthetic lupane triterpenoids betulin and betulinic acid derivatives: synergistic effects with miltefosineDifferent Mutations in a P-type ATPase Transporter in Leishmania Parasites are Associated with Cross-resistance to Two Leading Drugs by Distinct MechanismsMiltefosine increases lipid and protein dynamics in Leishmania amazonensis membranes at concentrations similar to those needed for cytotoxicity activity.N-butyl-[1-(4-methoxy)phenyl-9H-β-carboline]-3-carboxamide prevents cytokinesis in Leishmania amazonensisPhotodynamic effects of zinc phthalocyanines on intracellular amastigotes of Leishmania amazonensis and Leishmania braziliensis.Differences in antibiotic-induced oxidative stress responses between laboratory and clinical isolates of Streptococcus pneumoniae.The Oral Antimalarial Drug Tafenoquine Shows Activity against Trypanosoma brucei.Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana.Cos-Seq for high-throughput identification of drug target and resistance mechanisms in the protozoan parasite Leishmania.Genomic Appraisal of the Multifactorial Basis for In Vitro Acquisition of Miltefosine Resistance in Leishmania donovaniA new ABC half-transporter in Leishmania major is involved in resistance to antimony.Molecular characterization of the MRPA transporter and antimony uptake in four New World Leishmania spp. susceptible and resistant to antimony.Phosphorylation of Translation Initiation Factor 2-Alpha in Leishmania donovani under Stress Is Necessary for Parasite Survival.Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism.DNA repair pathways in trypanosomatids: from DNA repair to drug resistance.Deciphering the interplay between cysteine synthase and thiol cascade proteins in modulating Amphotericin B resistance and survival of Leishmania donovani under oxidative stress.Drug-resistant microorganisms with a higher fitness--can medicines boost pathogens?Experimental resistance to drug combinations in Leishmania donovani: metabolic and phenotypic adaptations.4-amino bis-pyridinium derivatives as novel antileishmanial agents.Development of an ex vivo lymph node explant model for identification of novel molecules active against Leishmania major.Up-regulation of silent information regulator 2 (Sir2) is associated with amphotericin B resistance in clinical isolates of Leishmania donovani.Mechanism of amphotericin B resistance in clinical isolates of Leishmania donovaniDeep-sequencing revealing mutation dynamics in the miltefosine transporter gene in Leishmania infantum selected for miltefosine resistance.Mitochondrial Proteomics of Antimony and Miltefosine Resistant Leishmania infantum.MAPK1 of Leishmania donovani modulates antimony susceptibility by downregulating P-glycoprotein efflux pumps.Zinc depletion promotes apoptosis-like death in drug-sensitive and antimony-resistance Leishmania donovaniQuantitative proteomic analysis of amphotericin B resistance in Leishmania infantum.Transcriptome profiling identifies genes/pathways associated with experimental resistance to paromomycin in Leishmania donovani.DNA damage is a late event in resveratrol-mediated inhibition of Escherichia coli.Multi-analytical platform metabolomic approach to study miltefosine mechanism of action and resistance in Leishmania.Miltefosine-unresponsive Leishmania donovani has a greater ability than miltefosine-responsive L. donovani to resist reactive oxygen species.A complex interplay between sphingolipid and sterol metabolism revealed by perturbations to the Leishmania metabolome caused by miltefosine.Oxidative Stress-Mediated Overexpression of Uracil DNA Glycosylase in Leishmania donovani Confers Tolerance against Antileishmanial Drugs.
P2860
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P2860
Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Tolerance to drug-induced cell ...... drug resistance in Leishmania.
@en
type
label
Tolerance to drug-induced cell ...... drug resistance in Leishmania.
@en
prefLabel
Tolerance to drug-induced cell ...... drug resistance in Leishmania.
@en
P2860
P356
P1476
Tolerance to drug-induced cell ...... drug resistance in Leishmania.
@en
P2093
P2860
P356
10.1038/CDDIS.2011.83
P577
2011-09-01T00:00:00Z