Predicting Cortisol Exposure from Paediatric Hydrocortisone Formulation Using a Semi-Mechanistic Pharmacokinetic Model Established in Healthy Adults.

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Predicting Cortisol Exposure from Paediatric Hydrocortisone Formulation Using a Semi-Mechanistic Pharmacokinetic Model Established in Healthy Adults.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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Predicting Cortisol Exposure f ...... Established in Healthy Adults.

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label

Predicting Cortisol Exposure f ...... Established in Healthy Adults.

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prefLabel

Predicting Cortisol Exposure f ...... Established in Healthy Adults.

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P1476

Predicting Cortisol Exposure f ...... Established in Healthy Adults

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P2093

Charlotte Kloft

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Johanna Melin

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Martin J Whitaker

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Richard J Ross

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Wilhelm Huisinga

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P2860

Congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency: an Endocrine Society clinical practice guideline

Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline

Is physiological glucocorticoid replacement important in children?

World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects

Hydrocortisone suspension and hydrocortisone tablets are not bioequivalent in the treatment of children with congenital adrenal hyperplasia.

PsN-Toolkit--a collection of computer intensive statistical methods for non-linear mixed effect modeling using NONMEM.

Changes in plasma protein binding have little clinical relevance.

Pharmacokinetic-pharmacodynamic studies of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor MK-0916 in healthy subjects.

Effect of dose size on the pharmacokinetics of intravenous hydrocortisone during endogenous hydrocortisone suppression.

Pharmacokinetic evidence for suboptimal treatment of adrenal insufficiency with currently available hydrocortisone tablets.

P2888

s40262-017-0575-8

P304

515-527

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scholarly article

P356

10.1007/S40262-017-0575-8

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P433

http://www.w3.org/2001/XMLSchema#string

P478

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P50

Zinnia P Parra-Guillen

Niklas Hartung

P577

2018-04-01T00:00:00Z

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P6179

1090938130

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P698

28762136

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P921

cortisol