Fluorinated Nucleotide Modifications Modulate Allele Selectivity of SNP-Targeting Antisense Oligonucleotides.

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2'β-Fluoro-Tricyclo Nucleic Acids (2'F-tc-ANA): Thermal Duplex Stability, Structural Studies, and RNase H Activation.

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Fluorinated Nucleotide Modifications Modulate Allele Selectivity of SNP-Targeting Antisense Oligonucleotides.

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Fluorinated Nucleotide Modific ...... ng Antisense Oligonucleotides.

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Fluorinated Nucleotide Modific ...... ng Antisense Oligonucleotides.

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Fluorinated Nucleotide Modific ...... ng Antisense Oligonucleotides.

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P1476

Fluorinated Nucleotide Modific ...... ng Antisense Oligonucleotides.

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P2093

Eric E Swayze

http://www.w3.org/2001/XMLSchema#string

Josh Nichols

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Michael E Jung

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Michael E Østergaard

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Punit P Seth

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Timothy A Dwight

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Walt Lima

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Structure of human RNase H1 complexed with an RNA/DNA hybrid: insight into HIV reverse transcription

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Synthesis and Antisense Properties of Fluoro Cyclohexenyl Nucleic Acid (F-CeNA), a Nuclease Stable Mimic of 2′-Fluoro RNA

Backbone FC-H···O hydrogen bonds in 2'F-substituted nucleic acids

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide

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RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform.

Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene / allele-specific silencing of mutant huntingtin.

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20-30

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scholarly article

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10.1016/J.OMTN.2017.02.001

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P478

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2017-02-09T00:00:00Z

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28624195

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5363678

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Fluorinated Nucleotide Modifications Modulate Allele Selectivity of SNP-Targeting Antisense Oligonucleotides.

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Fluorinated Nucleotide Modifications Modulate Allele Selectivity of SNP-Targeting Antisense Oligonucleotides.

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