The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway.
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Exonuclease hDIS3L2 specifies an exosome-independent 3'-5' degradation pathway of human cytoplasmic mRNAMammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAsThe organization and regulation of mRNA-protein complexesSurprises in the 3'-end: 'U' can decide too!Threading the barrel of the RNA exosomeProteins involved in the degradation of cytoplasmic mRNA in the major eukaryotic model systemsDeterminants and implications of mRNA poly(A) tail size--does this protein make my tail look big?Poly(A) polymerase (PAP) diversity in gene expression--star-PAP vs canonical PAPA critical switch in the enzymatic properties of the Cid1 protein deciphered from its product-bound crystal structureStructural analysis of Dis3l2, an exosome-independent exonuclease from Schizosaccharomyces pombeRNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targetingCytoplasmic mRNA turnover and ageingMechanisms of microRNA turnoverMechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathwayBroad and adaptable RNA structure recognition by the human interferon-induced tetratricopeptide repeat protein IFIT5Detection of 3'-end RNA uridylation with a protein nanopore.Global analysis of the nuclear processing of transcripts with unspliced U12-type introns by the exosome.mRNA stability in the nucleus.Eri1: a conserved enzyme at the crossroads of multiple RNA-processing pathways.A MicroRNA precursor surveillance system in quality control of MicroRNA synthesis.The RNase R from Campylobacter jejuni has unique features and is involved in the first steps of infection.Emerging roles for ribonucleoprotein modification and remodeling in controlling RNA fateUridylation by TUT4 and TUT7 marks mRNA for degradation.Apoptosis Triggers Specific, Rapid, and Global mRNA Decay with 3' Uridylated Intermediates Degraded by DIS3L2The mitochondrial RNA landscape of Saccharomyces cerevisiaeModulating the RNA processing and decay by the exosome: altering Rrp44/Dis3 activity and end-productDeep sequencing shows multiple oligouridylations are required for 3' to 5' degradation of histone mRNAs on polyribosomesAnalysis of RNA decay factor mediated RNA stability contributions on RNA abundance.Widespread exon skipping triggers degradation by nuclear RNA surveillance in fission yeastHigh-throughput sequencing of human plasma RNA by using thermostable group II intron reverse transcriptases.Oligoadenylation of 3' decay intermediates promotes cytoplasmic mRNA degradation in Drosophila cells.The 3'-5' exoribonuclease Dis3 regulates the expression of specific microRNAs in Drosophila wing imaginal discs.Small RNAs meet their targets: when methylation defends miRNAs from uridylationBiogenesis and regulation of the let-7 miRNAs and their functional implications.Antisense Transcripts Delimit Exonucleolytic Activity of the Mitochondrial 3' Processome to Generate Guide RNAs.Identification of factors involved in target RNA-directed microRNA degradation.Spatial control of translation repression and polarized growth by conserved NDR kinase Orb6 and RNA-binding protein Sts5Arabidopsis AtRRP44A is the functional homolog of Rrp44/Dis3, an exosome component, is essential for viability and is required for RNA processing and degradationTUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAsUridylation and adenylation of RNAs.
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P2860
The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway.
@en
type
label
The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway.
@en
prefLabel
The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway.
@en
P2860
P50
P356
P1433
P1476
The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway.
@en
P2093
Clémentine Dressaire
P2860
P304
P356
10.1038/EMBOJ.2013.63
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P50
P577
2013-03-15T00:00:00Z