Enhancing the catalytic repertoire of nucleic acids: a systematic study of linker length and rigidity.
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DNA-templated polymerization of side-chain-functionalized peptide nucleic acid aldehydesCleavage of adenine-modified functionalized DNA by type II restriction endonucleasesAmino-functionalized DNA: the properties of C5-amino-alkyl substituted 2'-deoxyuridines and their application in DNA triplex formationA new class of cleavable fluorescent nucleotides: synthesis and optimization as reversible terminators for DNA sequencing by synthesisDesign and synthesis of boronic-acid-labeled thymidine triphosphate for incorporation into DNA.In vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitorsCyDNA: synthesis and replication of highly Cy-dye substituted DNA by an evolved polymerase.DNA modification under mild conditions by Suzuki-Miyaura cross-coupling for the generation of functional probes.Challenging artificial genetic systems: thymidine analogs with 5-position sulfur functionality.Artificial specific binders directly recovered from chemically modified nucleic acid libraries.Functional tuning of nucleic acids by chemical modifications: tailored oligonucleotides as drugs, devices, and diagnostics.Synthesis and Enzymatic Incorporation of Modified Deoxyuridine Triphosphates.Nucleic Acid Bioconjugates in Cancer Detection and Therapy.A self-cleaving DNA enzyme modified with amines, guanidines and imidazoles operates independently of divalent metal cations (M2+).Site-specifically arraying small molecules or proteins on DNA using an expanded genetic alphabetSite-specific labeling of DNA and RNA using an efficiently replicated and transcribed class of unnatural base pairs.Versatile synthesis of amino acid functionalized nucleosides via a domino carboxamidation reaction.Nucleobase modified peptide nucleic acid.Enhancing the catalytic repertoire of nucleic acids. II. Simultaneous incorporation of amino and imidazolyl functionalities by two modified triphosphates during PCR.Structural Basis for the KlenTaq DNA Polymerase Catalysed Incorporation of Alkene- versus Alkyne-Modified Nucleotides.Systematic characterization of 2'-deoxynucleoside- 5'-triphosphate analogs as substrates for DNA polymerases by polymerase chain reaction and kinetic studies on enzymatic production of modified DNAIncorporation of reporter molecule-labeled nucleotides by DNA polymerases. II. High-density labeling of natural DNA.Sequence-specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities.Systematic analysis of enzymatic DNA polymerization using oligo-DNA templates and triphosphate analogs involving 2',4'-bridged nucleosides.Modified DNA bearing 5(methoxycarbonylmethyl)-2'-deoxyuridine: preparation by PCR with thermophilic DNA polymerase and postsynthetic derivatization.The "Corey's reagent," 3,5-di-tert-butyl-1,2-benzoquinone, as a modifying agent in the synthesis of fluorescent and double-headed nucleosides.Effect of imino group of a linker arm at the C5 position of a pyrimidine nucleoside on the thermal stabilities of DNA/DNA and DNA/RNA duplexes.Systematic study of constraints imposed by modified nucleoside triphosphates with protein-like side chains for use in in vitro selection.Modified nucleoside triphosphates: synthesis and applications for RNA in vitro selection.Comparative Study of Novel Fluorescent Cyanine Nucleotides: Hybridization Analysis of Labeled PCR Products Using a Biochip.A method for selecting modified DNAzymes without the use of modified DNA as a template in PCR.Protein-inspired modified DNAzymes: dramatic effects of shortening side-chain length of 8-imidazolyl modified deoxyadenosines in selecting RNaseA mimicking DNAzymes.A densely modified M2+-independent DNAzyme that cleaves RNA efficiently with multiple catalytic turnover.
P2860
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P2860
Enhancing the catalytic repertoire of nucleic acids: a systematic study of linker length and rigidity.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Enhancing the catalytic repert ...... of linker length and rigidity.
@en
type
label
Enhancing the catalytic repert ...... of linker length and rigidity.
@en
prefLabel
Enhancing the catalytic repert ...... of linker length and rigidity.
@en
P2093
P2860
P356
P1476
Enhancing the catalytic repert ...... of linker length and rigidity.
@en
P2093
Brazier JA
Dickman MJ
Gourlain T
Williams DM
P2860
P304
P356
10.1093/NAR/29.7.1565
P407
P577
2001-04-01T00:00:00Z