Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery.
about
An Overview of CRISPR-Based Tools and Their Improvements: New Opportunities in Understanding Plant-Pathogen Interactions for Better Crop ProtectionGenome-editing technologies for gene correction of hemophiliaShifting paradigms in restoration of the world's coral reefs.CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome.mCAL: A New Approach for Versatile Multiplex Action of Cas9 Using One sgRNA and Loci Flanked by a Programmed Target Sequence.A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular ResearchA genome editing primer for the hematologistEditing the epigenome: technologies for programmable transcription and epigenetic modulation.Gene Editing for Treatment of Neurological Infections.MEK1 is required for the development of NRAS-driven leukemia.Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis.Naturally Occurring Off-Switches for CRISPR-Cas9.CRISPR-Cas9: From a bacterial immune system to genome-edited human cells in clinical trials.CRISPR: express delivery to any DNA address.Microengineered cancer-on-a-chip platforms to study the metastatic microenvironment.Defining and improving the genome-wide specificities of CRISPR-Cas9 nucleases.CRISPR-Cas9 technology and its application in haematological disorders.Gene therapies that restore dystrophin expression for the treatment of Duchenne muscular dystrophy.Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity.Regulation of adult neural progenitor cell functions by purinergic signaling.Cornerstones of CRISPR-Cas in drug discovery and therapy.Precision genome editing in the CRISPR era.Targeted isolation and cloning of 100-kb microbial genomic sequences by Cas9-assisted targeting of chromosome segments.In trans paired nicking triggers seamless genome editing without double-stranded DNA cutting.Immunity to CRISPR Cas9 and Cas12a therapeutics.Breeding next generation tree fruits: technical and legal challenges.From Reductionism to Holism: Toward a More Complete View of Development Through Genome Engineering.Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses.Massively Parallel Biophysical Analysis of CRISPR-Cas Complexes on Next Generation Sequencing Chips.CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR-Cas9 nuclease off-targets.A novel experimental model for human mixed acinar-ductal pancreatic cancer.Cas9 loosens its grip on off-target sites.Genome editing: The domestication of Cas9.Designing Epigenome Editors: Considerations of Biochemical and Locus Specificities.All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivoOrthogonal Cas9-Cas9 chimeras provide a versatile platform for genome editing
P2860
Q26745534-CB095D71-84E7-4975-9273-3699092E355BQ28066273-6F515BF5-EB86-4C8E-A4B9-E11881F6BFB5Q31168436-8BE3E12C-9CE1-45E0-8092-B2F26236D598Q33766701-0B3CF522-D8EF-4591-8EB3-B1B3305B30B6Q36019453-80370AAD-8238-45D0-B32A-91DD769216FFQ36940626-677ED280-635D-4255-9833-630435FC52EFQ36942027-060DD574-39F9-40D9-8DA2-BFD56B3A8050Q37042113-E491BC64-9703-43EA-AE7D-91A7C94CEFB6Q37136471-DD3D06D0-A40F-48E6-9CD7-56F5C1C0D54FQ37696978-8A6F4124-B48B-441C-BA51-72D7D8450246Q38716194-7C53E0F5-6A92-478C-B254-2E683AD44B83Q38725824-5A8B4521-C383-42F4-8137-FCA31D0824F5Q38746615-30DC8B0B-7B8E-4D5A-A1A3-7D01A0308190Q38797121-67C9EA12-03BC-4EAF-A084-1B1BB3D96F19Q38810462-B5253BF6-C837-4926-8A7F-E6ECDE210BF0Q38810667-CED24104-B17E-4139-A5C5-84B57509BC63Q38822073-65A237C8-C22C-4CE1-BB94-6EB26AB246F5Q38829627-59C0E354-6CBF-4A5E-B996-55F9AE27F0B8Q38919610-A10887E9-87AC-441E-9A06-B2B5FF5F67FFQ38954776-E3BAACB3-1332-4C33-AE1D-02671EC4D12BQ39051110-C9004827-F11D-4821-B998-4533FF9668BAQ39126189-E1650BB4-A7FE-4D69-9D57-2FBFE6C91B9AQ40704645-63ED2C70-9605-476E-9D93-32F0E21290F8Q41689807-2A4B0E5F-4D6A-4EB7-9636-73206D16DAFCQ45873745-7D9E31AD-6868-4754-9F00-372C0FDCC75DQ46241586-DBE24E3E-C85D-4612-B539-F759B656D325Q47356373-DFB674EF-F593-4B16-BCD5-5CDAAA46A1A7Q47548145-2C0FE998-00A8-4D40-94F2-510085406B1CQ47969896-DBCF94DE-9B33-4ECF-B48D-9536143CC210Q48213026-F26F2595-D054-4298-861A-C6C415E05B07Q50141073-A9C59898-3C35-4C88-9ADD-12B422057E70Q51454074-4CBB5788-10B0-4837-A087-18A8A8BC5586Q51544327-9ACBCC80-E756-4345-9542-FAC6880E9A0AQ52360880-0872A085-5683-4473-B453-E90854F59E4FQ58324031-7281E058-E846-4F0D-BBDC-D9F0D39C2D4CQ59134751-E56A481A-9598-4031-94B3-15497FD2C962
P2860
Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery.
@en
type
label
Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery.
@en
prefLabel
Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery.
@en
P2093
P2860
P356
P1433
P1476
Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery.
@en
P2093
Ankit Gupta
Mehmet Fatih Bolukbasi
Scot A Wolfe
P2860
P2888
P356
10.1038/NMETH.3684
P577
2015-12-01T00:00:00Z
P6179
1001208933